Evidence map›Paper›PMID 37805095›Full record

ArticleJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2023

Computer versus human-expert ranking of posterior pole vascular tortuosity and dilation using retinal vessel maps generated from bedside optical coherence tomography: a proof-of-concept study.

Kai R Seely, Sharon F Freedman, Sara Grace, Marguerite C Weinert, Gloria J Hong, Cynthia A Toth, S Grace Prakalapakorn

Abstract readCase Reports
In one paragraph

Article in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kai R SeelyDepartment of Ophthalmology, Duke University Medical Center, Durham, North Carolina.
Sharon F FreedmanDepartment of Ophthalmology, Duke University Medical Center, Durham, North Carolina; Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
Sara GraceDepartment of Ophthalmology, Duke University Medical Center, Durham, North Carolina.
Marguerite C WeinertBoston Children's Hospital, Boston, Massachusetts; Department of Ophthalmology, Harvard School of Medicine, Boston, Massachusetts.
Gloria J HongDepartment of Ophthalmology, Duke University Medical Center, Durham, North Carolina.
Cynthia A TothDepartment of Ophthalmology, Duke University Medical Center, Durham, North Carolina; Department of Biomedical Engineering, Duke University, Durham, North Carolina.
S Grace PrakalapakornDepartment of Ophthalmology, Duke University Medical Center, Durham, North Carolina; Department of Pediatrics, Duke University Medical Center, Durham, North Carolina. Electronic address: grace.prakalapakorn@duke.edu.

Funding

Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve CareR01EY025009 · NEI · DUKE UNIVERSITY · PI Xi Chen, CYNTHIA ANN TOTH · 2016 to 2026
$6.6M
NRSA Training CoreTL1TR002555 · NCATS · DUKE UNIVERSITY · PI EDELMAN, DAVID · 2018 to 2022
$3.7M
Secondary Data Analysis for Neonates with Retinal OCT ImagingR21EY034138 · NEI · DUKE UNIVERSITY · PI TOTH, CYNTHIA ANN, YING, GUI-SHUANG · 2022 to 2023
$459k
NCATS NIH HHS TL1 TR002555NEI NIH HHS R01 EY025009NEI NIH HHS R21 EY034138
6 · The paper itself

Abstract

Semiautomated computer software (ie, ROPtool) can trace and analyze optical coherence tomography (OCT)-generated retinal vessel maps for plus/pre-plus disease with high reliability and accuracy. This proof-of-concept study found that ROPtool can reliably rank OCT-generated vessel maps for tortuosity and combined tortuosity/dilation, which correlated well with human-expert rankings and clinical examination.

Indexed as

Diagnosis, Computer-AssistedRetinopathy of PrematurityComputersDilatationDilatation, PathologicHumansInfant, NewbornReproducibility of ResultsRetinal VesselsTomography, Optical Coherence

Identifiers

PMID37805095
PMCPMC10842607

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.