Evidence map›Paper›PMID 37804833›Full record

ReviewNeuron2023

Deep-brain optical recording of neural dynamics during behavior.

Zhe Charles Zhou, Adam Gordon-Fennell, Sean C Piantadosi, Na Ji, Spencer LaVere Smith, Michael R Bruchas, Garret D Stuber

Abstract readReview
In one paragraph

Review in Neuron, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Fabrication of High-Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
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  11. Review
  12. Article
  13. Review
  14. Identifying dysfunctional cell types and circuits in animal models for psychiatric disorders with calcium imaging.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  15. Article
  16. Review
  17. An opponent striatal circuit for distributional reinforcement learning.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhe Charles ZhouDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, USA; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA 98195, USA.
Adam Gordon-FennellDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, USA; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA 98195, USA.
Sean C PiantadosiDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, USA; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA 98195, USA.
Na JiDepartment of Physics, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Spencer LaVere SmithDepartment of Electrical and Computer Engineering, University of California Santa Barbara, Santa Barbara, CA 93106, USA.
Michael R BruchasDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, USA; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA 98195, USA; Department of Pharmacology, University of Washington, Seattle, WA 98195, USA; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA. Electronic address: mbruchas@uw.edu.
Garret D StuberDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, USA; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA 98195, USA; Department of Pharmacology, University of Washington, Seattle, WA 98195, USA. Electronic address: gstuber@uw.edu.

Funding

Validating Theoretical Models with Neurophysiology and OptogeneticsU19NS107613 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JI, NA · 2018 to 2022
$16.7M
University of Washington Center of Excellence in Opioid Addiction ResearchP30DA048736 · NIDA · UNIVERSITY OF WASHINGTON · PI Charles Chavkin · 2019 to 2026
$13.0M
TRAINING IN THE MOLECULAR PHARMACOLOGY OF ABUSED DRUGST32DA007278 · NIDA · UNIVERSITY OF WASHINGTON · PI Susan Marie Ferguson, Paul E. M. Phillips · 1993 to 2026
$9.8M
Decoding Locus Coeruleus Neural Circuits and Signaling In Negative AffectR01MH112355 · NIMH · WASHINGTON UNIVERSITY · PI Michael R. Bruchas · 2016 to 2026
$5.3M
Neural circuit elements that orchestrate cue-reward associationsR37DA032750 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Garret D Stuber · 2017 to 2026
$4.5M
Anesthesiology & Perioperative Medicine Training GrantT32GM086270 · NIGMS · UNIVERSITY OF WASHINGTON · PI Tonya M Palermo · 2009 to 2026
$4.3M
Lateral Hypothalamic Circuits for Feeding and ReinforcementR01DA038168 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STUBER, GARRET D · 2014 to 2025
$4.0M
DISSECTING DYNORPHIN-KAPPA OPIOID MEDIATED REINSTATEMENT OF NICOTINE PREFERENCER37DA033396 · NIDA · WASHINGTON UNIVERSITY · PI Michael R. Bruchas · 2018 to 2026
$3.8M
High-Speed Volumetric Imaging of Neural Activity throughout the Living Brain - Supplement RequestU01NS103489 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI JI, NA · 2017 to 2019
$2.7M
Transcriptional, functional, and circuit profiling at single cell resolution of neuronal ensembles engaged by heroin relapseR01DA054317 · NIDA · UNIVERSITY OF WASHINGTON · PI FERGUSON, SUSAN MARIE, STUBER, GARRET D · 2021 to 2025
$2.7M
Adaptive optical microscopy for high-accuracy recording of neural activity in vivoU01NS118300 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI JI, NA · 2021 to 2023
$1.7M
Investigation into the role of lateral hypothalamus GABA and glutamate relative dynamics in encoding affective valence and modulating motivated behaviorsF32DA054719 · NIDA · UNIVERSITY OF WASHINGTON · PI GORDON-FENNELL, ADAM G · 2022 to 2022
$70k
NIDA NIH HHS F32 DA054719NIDA NIH HHS P30 DA048736NIDA NIH HHS R01 DA038168NIDA NIH HHS R01 DA054317NIDA NIH HHS R37 DA032750NIDA NIH HHS R37 DA033396NIDA NIH HHS T32 DA007278NIGMS NIH HHS T32 GM086270NIMH NIH HHS R01 MH112355NINDS NIH HHS U01 NS103489NINDS NIH HHS U01 NS118300NINDS NIH HHS U19 NS107613
6 · The paper itself

Abstract

In vivo fluorescence recording techniques have produced landmark discoveries in neuroscience, providing insight into how single cell and circuit-level computations mediate sensory processing and generate complex behaviors. While much attention has been given to recording from cortical brain regions, deep-brain fluorescence recording is more complex because it requires additional measures to gain optical access to harder to reach brain nuclei. Here we discuss detailed considerations and tradeoffs regarding deep-brain fluorescence recording techniques and provide a comprehensive guide for all major steps involved, from project planning to data analysis. The goal is to impart guidance for new and experienced investigators seeking to use in vivo deep fluorescence optical recordings in awake, behaving rodent models.

Indexed as

BrainNeurons

Identifiers

PMID37804833
PMCPMC10843303

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.