Evidence map›Paper›PMID 37804449›Full record

ArticleInternational journal of colorectal disease2023

Quality of life after prophylactic surgery for colorectal adenomatous polyposis.

Emanuele Rausa, Chiara Maura Ciniselli, Stefano Signoroni, Laura Sophie Boer, Loïs Oldhoff, Laura Dijk, Franka Van Luijk, Maria Teresa Ricci, Chiara Ghidoli, Valeria Duroni and 6 more

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Article in International journal of colorectal disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Emanuele Rausa *Unit of Hereditary Digestive Tract Tumours, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Chiara Maura Ciniselli *Unit of Bioinformatics and Biostatistics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Stefano SignoroniUnit of Hereditary Digestive Tract Tumours, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. stefano.signoroni@istitutotumori.mi.it.
Laura Sophie BoerDepartment of Medical Sciences, University of Groningen, Groningen, Netherlands.
Loïs OldhoffDepartment of Medical Sciences, University of Groningen, Groningen, Netherlands.
Laura DijkDepartment of Medical Sciences, University of Groningen, Groningen, Netherlands.
Franka Van LuijkDepartment of Medical Sciences, University of Groningen, Groningen, Netherlands.
Maria Teresa RicciUnit of Hereditary Digestive Tract Tumours, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Chiara GhidoliUnit of Hereditary Digestive Tract Tumours, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Valeria DuroniUnit of Bioinformatics and Biostatistics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Clorinda BrignolaUnit of Hereditary Digestive Tract Tumours, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Claudia BorreaniClinical Psychology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Sara AlfieriClinical Psychology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Giovanni ApoloneScientific Directorate, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Paolo VerderioUnit of Bioinformatics and Biostatistics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Marco VitellaroUnit of Hereditary Digestive Tract Tumours, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeColorectal adenomatous polyposis is characterized by the onset of tens to thousands of adenomas in the colorectal epithelium and, if not treated, leads to a lifetime increased risk of developing colorectal cancer compared to the general population. Thus, prophylactic surgery is recommended. This study aims to investigate the quality of life of colorectal adenomatous polyposis patients following prophylactic surgery and indirectly compares these findings with those of healthy adults of the normative sample.

methodsAll patients who underwent prophylactic surgery for polyposis and were in follow-up at the hereditary digestive tract tumors outpatient department of our institute were eligible for the study. The Short Form-36 questionnaire and 21 ad hoc items were used at the time of clinical evaluation.

resultsA total of 102 patients were enrolled. For the SF-36 domains, mean values ranged from 64.18 for vitality to 88.49 for physical functioning, with the highest variability for role-physical limitations; the minimum value of functioning was reached for role-physical limitations, role-emotional limitations, and social functioning. The maximum value of functioning was reached for role-emotional limitations (73.96%) and role-physical limitations (60.42%). In total, 48.96% and 90.63% of patients reported no fecal or urinary incontinence episodes, respectively; 69.79% of patients did not have problems in work/school resumption or the personal sexual sphere.

conclusionQuality of life following prophylactic surgery for these patients seems to be good when indirectly compared to HP-normative samples'. Young adult patients appear to quickly manage and adapt to changes in bowel functioning. A minority of patients may experience social and sexual issues.

Indexed as

Adenomatous Polyposis ColiColorectal NeoplasmsProctocolectomy, RestorativeColectomyHumansQuality of LifeColorectal adenomatous polyposisPostoperative bowel functionQuality of lifeTotal colectomy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.