Evidence map›Paper›PMID 37803889›Full record

ArticleMaternal & child nutrition2024

Risk factors for anaemia among women and their young children hospitalised with suspected thiamine deficiency in northern Lao PDR.

Sonja Y Hess, Taryn J Smith, Dalaphone Sitthideth, Charles D Arnold, Xiuping Tan, Kerry S Jones, Kenneth H Brown, Silvia Alayon, Sengchanh Kounnavong

Open access · goldAbstract read
In one paragraph

Article in Maternal & child nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. The value of an ecological approach to address micronutrient malnutrition.The American journal of clinical nutrition · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Sonja Y HessInstitute for Global Nutrition and Department of Nutrition, University of California Davis, Davis, California, USA.ORCID 0000-0002-4661-277X
Taryn J SmithInstitute for Global Nutrition and Department of Nutrition, University of California Davis, Davis, California, USA.ORCID 0000-0001-9543-6461
Dalaphone SitthidethLao Tropical and Public Health Institute, Vientiane, Lao People's Democratic Republic.
Charles D ArnoldInstitute for Global Nutrition and Department of Nutrition, University of California Davis, Davis, California, USA.
Xiuping TanInstitute for Global Nutrition and Department of Nutrition, University of California Davis, Davis, California, USA.
Kerry S JonesNutritional Biomarker Laboratory, MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Kenneth H BrownInstitute for Global Nutrition and Department of Nutrition, University of California Davis, Davis, California, USA.
Silvia AlayonUSAID Advancing Nutrition, Arlington, Virginia, USA.ORCID 0000-0002-8023-5023
Sengchanh KounnavongLao Tropical and Public Health Institute, Vientiane, Lao People's Democratic Republic.
University of California, Davis · USNational Institute of Public Health · LASave the Children · USUniversity of Cambridge · GB

Funding

Bill and Melinda Gates FoundationUnited States Agency for International Development 7200AA18C00070
6 · The paper itself

Abstract

Anaemia among women and young children remains a major public health concern. This secondary study describes the anaemia prevalence among young hospitalised children and their mothers in northern Lao People's Democratic Republic and explores possible nutritional causes and risk factors for anaemia. Hospitalised children (ages 21 days to <18 months) with clinical symptoms suggestive of thiamine deficiency disorders were eligible along with their mothers. Venous blood was collected for determination of haemoglobin, ferritin, soluble transferrin receptor (sTfR), retinol-binding protein (RBP), erythrocyte glutathione reductase activation coefficient (EGRac), thiamine diphosphate (ThDP) and acute phase proteins. Risk factors for anaemia were modelled using minimally adjusted logistic regression controlling for age. Haemoglobin results were available for 436 women (mean ± SD age 24.7 ± 6.4 years; 1.6% pregnant) and 427 children (4.3 ± 3.5 months; 60.3% male). Anaemia prevalence (Hb < 120 g/L for nonpregnant women and <110 g/L for pregnant women and children) was 30.7% among women and 55.2% among children. In bivariate analyses, biomarkers significantly associated with anaemia in women were ferritin, sTfR, RBP, EGRac and ThDP. Other risk factors for women were lower BMI, mid-upper arm circumference < 23.5 cm, lower education, lower socioeconomic index, food insecurity, Hmong ethnicity, not/rarely having attended antenatal care, not having taken antenatal iron-containing supplements and not meeting minimum dietary diversity. Risk factors for anaemia among children were older age, male sex, stunting, sTfR, ThDP and alpha-1-acid-glycoprotein. Anaemia was common among women and their hospitalised children and was associated with micronutrient deficiencies and socioeconomic, dietary and health care-seeking risk factors, suggesting that multiple strategies are required to prevent anaemia among women and children.

Indexed as

AnemiaAnemia, Iron-DeficiencyThiamine DeficiencyAdultFemaleFerritinsHemoglobinsHumansLaosMalePregnancyPrevalenceRisk FactorsSoutheast Asian PeopleYoung AdultFerritinsHemoglobinsanaemiairon deficiencyLaosriboflavin deficiencythiamine deficiency

Identifiers

PMID37803889
PMCPMC10749997
OpenAlexW4387420658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.