ArticleScientific reports2023
The relationship between albumin corrected anion gap levels and mortality in patients with asthma in the ICU.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Article
- Association between albumin-corrected anion gap and in-hospital mortality in ICU patients with lung cancer: a retrospective cohort study based on the MIMIC database.Journal of thoracic disease · 2026Article
- Increased serum albumin corrected anion gap levels are associated with poor prognosis in sepsis-induced coagulopathy patients.PloS one · 2026Article
- Neutrophil Percentage-to-Albumin Ratio: Unveiling a New Perspective on Mortality Risk in Intensive Care Unit Asthma Patients-A Retrospective Cohort Study.Mediators of inflammation · 2026Article
- Association between albumin-corrected anion gap and 60-day all-cause mortality in critically ill shock patients.European journal of medical research · 2025Article
- Association of albumin-corrected anion gap with all-cause and cardiovascular mortality in overactive bladder patients.Scientific reports · 2025Article
- Albumin-corrected anion gap and risk of mortality among US adults.Archives of public health = Archives belges de sante publique · 2025Article
- Association between albumin-corrected anion gap and delirium in acute pancreatitis: insights from the MIMIC-IV database.BMC gastroenterology · 2025Article
- Non-linear association between anion gap and 28-day mortality in critically ill patients with COVID-19: a cohort study from MIMIC IV database.Journal of thoracic disease · 2025Article
- Anion gap predicting 90-Day mortality and guiding furosemide use in ARDS.Scientific reports · 2025Article
- Prognostic significance of albumin corrected anion gap in patients with acute pancreatitis: a novel perspective.Scientific reports · 2025Article
- Relationship between albumin-corrected anion gap and lumbar spine bone mineral density: a cross-sectional study.Frontiers in aging · 2025Article
- Prognostic Value of the Albumin Corrected Anion Gap in ICU Patients with Chronic Obstructive Pulmonary Disease and Sepsis: A MIMIC-IV Cohort Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Article
- Article
- Article
- Independent prognostic importance of the albumin-corrected anion gap in critically ill patients with congestive heart failure: a retrospective study from MIMIC-IV database.BMC cardiovascular disorders · 2024Article
- Association of albumin-corrected anion gap with severe consciousness disorders and outcomes in ischemic stroke: a retrospective MIMIC analysis.Scientific reports · 2024Article
- Association between serum anion gap and 28-day mortality in critically ill patients with infective endocarditis: a retrospective cohort study from MIMIC IV database.BMC cardiovascular disorders · 2024Article
- Association between the anion gap and mortality in critically ill patients with influenza: A cohort study.Heliyon · 2024Article
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4 authors.
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Abstract
Although previous studies have suggested that albumin-corrected anion gap (ACAG) may be a predictor of mortality in critically ill patients in intensive care unit (ICU), its utility in the context of asthma has not been definitively established. In this study, baseline data, albumin concentration, anion gap (AG) and 30-d mortality data were retrieved from the Medical Information Mart for Intensive Care IV database (MIMIC-IV) for patients with asthma in the intensive care unit. Receiver operating characteristic (ROC) curves were constructed to analyze the predictive ability of ACAG and AG. The risk of 30-day mortality among patients with ACAG and asthma was analyzed using a restricted cubic spline (RCS) plot. Decision curve analysis (DCA) was used to evaluate the clinical usefulness of ACAG as a prognostic factor for 30-day mortality. Subsequently, subgroup analysis was conducted to explore potential variations in the relationship between ACAG and 30-day mortality based on factors such as sex, age, whether the asthma was acute, and other co-morbidities. Our study reveals that ACAG is a significant independent predictor of 30-day mortality in asthmatic patients receiving intensive care. The area under the AUC curve for ACAG was found to be 0.703, which is higher than that of AG, indicating that ACAG has a better predictive ability for 30-day mortality in this population. Furthermore, higher levels of ACAG were found to be associated with increased risk of 30-day mortality in asthmatic patients. In addition, decision curve analysis (DCA) demonstrated that the net benefit of ACAG was greater than that of AG. These findings suggest that ACAG may be a valuable prognostic factor for predicting 30-day mortality in asthmatic patients in the ICU. Our study provides evidence that ACAG is associated with an increased risk of 30-d mortality and has better predictive value in patients with combined asthma who are admitted to the ICU than AG.
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