Evidence map›Paper›PMID 37802613›Full record

ArticleBMJ open2023

Promoting Empathy and Affiliation in Relationships (PEAR) study: protocol for a longitudinal study investigating the development of early childhood callous-unemotional traits.

Nicholas Wagner, Emily Perkins, Yuheiry Rodriguez, Cora Ordway, Michaela Flum, Lucia Hernandez-Pena, Polina Perelstein, Kathy Sem, Yael Paz, Rista Plate and 9 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 2 countries.

Nicholas WagnerDepartment of Brain & Psychological Science, Boston University, Boston, Massachusetts, USA.
Emily PerkinsDepartment of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-3473-8962
Yuheiry RodriguezDepartment of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Cora OrdwayDepartment of Brain & Psychological Science, Boston University, Boston, Massachusetts, USA.
Michaela FlumDepartment of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Lucia Hernandez-PenaDepartment of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-9865-8067
Polina PerelsteinDepartment of Brain & Psychological Science, Boston University, Boston, Massachusetts, USA.
Kathy SemDepartment of Brain & Psychological Science, Boston University, Boston, Massachusetts, USA.
Yael PazDepartment of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Rista PlateDepartment of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ayomide PopoolaDepartment of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Sarah LynchDepartment of Brain & Psychological Science, Boston University, Boston, Massachusetts, USA.
Kristina AstoneBiostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0002-7305-7732
Ethan GoldsteinBiostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, Massachusetts, USA.
Wanjikũ F M NjorogeDepartment of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Adriane RaineDepartment of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Donna PincusDepartment of Brain & Psychological Science, Boston University, Boston, Massachusetts, USA.
Koraly Pérez-EdgarThe Pennsylvania State University, University Park, Pennsylvania, USA.
Rebecca WallerDepartment of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA rwaller@sas.upenn.edu.ORCID 0000-0002-5069-1183
University of Pennsylvania · USBoston University · USChildren's Hospital of Philadelphia · USPennsylvania State University · US

Funding

Risky Parenting and Temperament Pathways To Callous-Unemotional Traits In Early ChildhoodR01MH125904 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Nicholas J Wagner, Rebecca Waller · 2022 to 2026
$3.9M
NIMH NIH HHS R01 MH125904
6 · The paper itself

Abstract

introductionChildren with callous-unemotional (CU) traits are at high lifetime risk of antisocial behaviour. Low affiliation (ie, social bonding difficulties) and fearlessness (ie, low threat sensitivity) are proposed risk factors for CU traits. Parenting practices (eg, harshness and low warmth) also predict risk for CU traits. However, few studies in early childhood have identified attentional or physiological markers of low affiliation and fearlessness. Moreover, no studies have tested whether parenting practices are underpinned by low affiliation or fearlessness shared by parents, which could further shape parent-child interactions and exacerbate risk for CU traits. Addressing these questions will inform knowledge of how CU traits develop and isolate novel parent and child targets for future specialised treatments for CU traits. METHODS AND ANALYSIS: The Promoting Empathy and Affiliation in Relationships (PEAR) study aims to establish risk factors for CU traits in children aged 3-6 years. The PEAR study will recruit 500 parent-child dyads from two metropolitan areas of the USA. Parents and children will complete questionnaires, computer tasks and observational assessments, alongside collection of eye-tracking and physiological data, when children are aged 3-4 (time 1) and 5-6 (time 2) years. The moderating roles of child sex, race and ethnicity, family and neighbourhood disadvantage, and parental psychopathology will also be assessed. Study aims will be addressed using structural equation modelling, which will allow for flexible characterisation of low affiliation, fearlessness and parenting practices as risk factors for CU traits across multiple domains. ETHICS AND DISSEMINATION: Ethical approval was granted by Boston University (#6158E) and the University of Pennsylvania (#850638). Results will be disseminated through conferences and open-access publications. All study and task materials will be made freely available on lab websites and through the Open Science Framework (OSF).

Indexed as

Conduct DisorderEmpathyAntisocial Personality DisorderChild, PreschoolEmotionsFemaleHumansLongitudinal StudiesMaleParentingImpulse control disordersPersonality disordersPSYCHIATRY

Identifiers

PMID37802613
PMCPMC10565261
OpenAlexW4387439569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.