ArticleUrology2024
Epidemiology of Infantile Ureteropelvic Junction Obstruction in the US.
Article in Urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- A comparative analysis of retroperitoneal small-incision open pyeloplasty and laparoscopic pyeloplasty for infantile hydronephrosis.Pediatric surgery international · 2026Article
- Comparative Outcomes of Robot-Assisted and Laparoscopic Pyeloplasty in Infants and Toddlers: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2026Review
- Urinary Microbiome Dysbiosis in Children With Congenital Uropathies at Varying Risk for Urinary Tract Infections.Kidney international reports · 2026Article
- Children with recurrent urinary tract infections: who are they and why do we need better prevention options?BMC pediatrics · 2025Article
- Comparative analysis of laparoscopic and transumbilical incision open pyeloplasty for treatment of infants with ureteropelvic junction obstruction: a clinical efficacy and safety study.Translational pediatrics · 2025Article
- Pelvic Ectopic Kidney in an Adult: Robotic-Assisted Surgical Treatment of Unrecognized Ureteropelvic Junction Obstruction.Case reports in surgery · 2025Article
- Surgical intervention and long-term renal outcomes of congenital ureteropelvic junction obstruction in a young adult cohort.International urology and nephrology · 2024Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo describe sex- and diagnosis-specific comorbidities, outcomes, and secular trends associated with ureteropelvic junction obstruction (UPJO) in a large, real-world population diagnosed with hydronephrosis in infancy. MATERIALS AND
methodsWe identified all infants ≤1 year old with ≥1 claim in the Optum Clinformatics 2007-2020 nationwide population database and used univariable and multivariable Cox regression analyses to estimate associations of demographic and clinical characteristics of infants with a UPJO diagnosis with surgical status.
resultsOf 22,349 infants with hydronephrosis (1.1% of infants; males-1.4%, females-0.7%), 1722 (7.7%; 7.9%-males, 7.2%-females) had UPJO. Follow-up was ≥1 year in 1198 (70%) and ≥3 years in 555 (32%) cases, and UPJO repair was performed in 542 children (31.5%; 32.3%-males, 29.5%-females); 77.7% within 1 year and 97.3% within 3 years. UPJO repair was associated with prior urinary tract infection (UTI) (hazard ratio (HR) 1.41, 95% confidence interval (CI) 1.12-1.76) and South (HR 1.42, 95% CI 1.14-1.78) or Midwest (HR 1.60, 95% CI 1.26-2.04) geographic region but did not change over time.
conclusionThis population-based study provides a real-world view of postnatally diagnosed hydronephrosis, focusing on UPJO, for which 522 cases (∼1/3) had ≥3 years continuous coverage. UPJO-associated comorbidities were more common in females, and the frequencies of UPJO-associated surgery and comorbidities were higher than in other studies. Other than UTI, no other associated kidney or urinary tract diagnoses were associated with UPJO repair. We identified unique sex- and diagnosis-specific differences in associated comorbidities and interventions in children diagnosed with UPJO in the first year of life.
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