Evidence map›Paper›PMID 37802082›Full record

ReviewInternational journal of sports medicine2024

Exercise and Atrial Fibrillation: The Dose Makes the Poison? A Narrative Review.

Jonas Zacher, Karlo Filipovic, Georg Predel, Thomas Schmidt

Abstract readReview
In one paragraph

Review in International journal of sports medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Metabolic and Inflammatory Mechanisms Driving Atrial Fibrillation.Annual review of pharmacology and toxicology · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jonas ZacherInstitute of Cardiology and Sports Medicine, Preventative and Rehabilitative Sports and Performance Medicine, German Sport University Cologne, Köln, Germany.ORCID 0000-0002-9687-5746
Karlo FilipovicDepartment of Electrophysiology, University of Cologne, Heart Center, Uniklinik Köln, Köln, Germany.
Georg PredelInstitute of Cardiology and Sports Medicine, Preventative and Rehabilitative Sports and Performance Medicine, German Sport University Cologne, Köln, Germany.
Thomas SchmidtInstitute of Cardiology and Sports Medicine, Preventative and Rehabilitative Sports and Performance Medicine, German Sport University Cologne, Köln, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

"All things are poison, and nothing is without poison; the dosage alone makes it so a thing is not a poison" (Paracelsus, ~ 1538 AD). This well-known quote seems to aptly summarize the current understanding of the interaction between exercise and atrial fibrillation (AF). A host of data strongly suggests that regular exercise has a protective effect against developing AF. A small but well-conducted group of trials also demonstrates beneficial effects of exercise in the treatment of AF. Recently, however, potentially detrimental effects of large volumes of high-intensity exercise on the probability of developing AF have moved into the sports-cardiological focus. This effect is well documented for elite athletes; data regarding the general population is less clear. This review presents the current data regarding the protective, therapeutic and potentially risk-enhancing effects of exercise regarding AF. The authors demonstrate that the benefits are clear and strongly outweigh the potential disadvantages.

Indexed as

Atrial FibrillationPoisonsSportsAthletesExerciseHumansPoisons

Identifiers

PMID37802082
PMCPMC10776210

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.