Evidence map›Paper›PMID 37801198›Full record

ArticleLa Radiologia medica2023

Radiomics and artificial intelligence analysis by T2-weighted imaging and dynamic contrast-enhanced magnetic resonance imaging to predict Breast Cancer Histological Outcome.

Antonella Petrillo, Roberta Fusco, Maria Luisa Barretta, Vincenza Granata, Mauro Mattace Raso, Annamaria Porto, Eugenio Sorgente, Annarita Fanizzi, Raffaella Massafra, Miria Lafranceschina and 14 more

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Article in La Radiologia medica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 7 institutions in 1 country.

Antonella Petrillo *Radiology Division, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131, Naples, Italy. a.petrillo@istitutotumori.na.it.
Roberta Fusco *Medical Oncology Division, Igea SpA, 80013, Naples, Italy.
Maria Luisa BarrettaRadiology Division, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131, Naples, Italy.
Vincenza GranataRadiology Division, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131, Naples, Italy.
Mauro Mattace RasoRadiology Division, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131, Naples, Italy.
Annamaria PortoRadiology Division, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131, Naples, Italy.
Eugenio SorgenteRadiology Division, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131, Naples, Italy.
Annarita FanizziDirezione Scientifica-IRCCS, Istituto Tumori Giovanni Paolo II-Via Orazio Flacco 65, 70124, Bari, Italy.
Raffaella MassafraSSD Fisica Sanitaria-IRCCS Istituto Tumori Giovanni Paolo II-Via Orazio Flacco 65, 70124, Bari, Italy.
Miria LafranceschinaStruttura Semplice Dipartimentale di Radiodiagnostica Senologica-IRCCS Istituto Tumori Giovanni Paolo II-Via Orazio Flacco 65, 70124, Bari, Italy.
Daniele La ForgiaStruttura Semplice Dipartimentale di Radiodiagnostica Senologica-IRCCS Istituto Tumori Giovanni Paolo II-Via Orazio Flacco 65, 70124, Bari, Italy.
Charlotte Marguerite Lucille TrombadoriDipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168, Rome, Italy.
Paolo BelliDipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168, Rome, Italy.
Giovanna TrecateDepartment of Radiodiagnostic and Magnetic Resonance, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133, Milan, Italy.
Chiara TenconiDepartment of Medical Physics, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133, Milan, Italy.
Maria Carmen De SantisDe Santis Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133, Milan, Italy.
Laura GrecoRadiology and Diagnostic Imaging, Istituto di Ricovero E Cura a Carattere Scientifico (IRCCS) Regina Elena National Cancer Institute, Rome, Italy.
Francesca Romana FerrantiRadiology and Diagnostic Imaging, Istituto di Ricovero E Cura a Carattere Scientifico (IRCCS) Regina Elena National Cancer Institute, Rome, Italy.
Valeria De SoccioRadiology and Diagnostic Imaging, Istituto di Ricovero E Cura a Carattere Scientifico (IRCCS) Regina Elena National Cancer Institute, Rome, Italy.
Antonello VidiriRadiology and Diagnostic Imaging, Istituto di Ricovero E Cura a Carattere Scientifico (IRCCS) Regina Elena National Cancer Institute, Rome, Italy.
Francesca BottaBreast Imaging Division, IEO Istituto Europeo di Oncologia, 20141, Milan, Italy.
Valeria DominelliBreast Imaging Division, IEO Istituto Europeo di Oncologia, 20141, Milan, Italy.
Enrico CassanoBreast Imaging Division, IEO Istituto Europeo di Oncologia, 20141, Milan, Italy.
Luca BoldriniDipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168, Rome, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITEuropean Institute of Oncology · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITAgostino Gemelli University Polyclinic · ITIGEA Clinical Biophysics (Italy) · ITIstituto Tumori Bari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of the study was to evaluate the accuracy of radiomics features obtained by MR images to predict Breast Cancer Histological Outcome.

methodsA total of 217 patients with malignant lesions were analysed underwent MRI examinations. Considering histological findings as the ground truth, four different types of findings were used in both univariate and multivariate analyses: (1) G1 + G2 vs G3 classification; (2) presence of human epidermal growth factor receptor 2 (HER2 + vs HER2 -); (3) presence of the hormone receptor (HR + vs HR -); and (4) presence of luminal subtypes of breast cancer.

resultsThe best accuracy for discriminating HER2 + versus HER2 - breast cancers was obtained considering nine predictors by early phase T1-weighted subtraction images and a decision tree (accuracy of 88% on validation set). The best accuracy for discriminating HR + versus HR - breast cancers was obtained considering nine predictors by T2-weighted subtraction images and a decision tree (accuracy of 90% on validation set). The best accuracy for discriminating G1 + G2 versus G3 breast cancers was obtained considering 16 predictors by early phase T1-weighted subtraction images in a linear regression model with an accuracy of 75%. The best accuracy for discriminating luminal versus non-luminal breast cancers was obtained considering 27 predictors by early phase T1-weighted subtraction images and a decision tree (accuracy of 94% on validation set).

conclusionsThe combination of radiomics analysis and artificial intelligence techniques could be used to support physician decision-making in prediction of Breast Cancer Histological Outcome.

Indexed as

Breast NeoplasmsArtificial IntelligenceFemaleHumansMagnetic Resonance ImagingRetrospective StudiesArtificial intelligenceBreast cancerMagnetic resonance imagingRadiomics

Identifiers

PMID37801198
OpenAlexW4387393259

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.