Evidence map›Paper›PMID 37800635›Full record

ArticleCancer medicine2023

Body mass index and waist circumference in relation to risk of recurrence and progression after non-muscle invasive bladder cancer.

Moniek van Zutphen, Ivy Beeren, Katja K H Aben, Antoine G van der Heijden, J Alfred Witjes, Lambertus A L M Kiemeney, Alina Vrieling

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Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Moniek van ZutphenDepartment for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-2368-0606
Ivy BeerenDepartment for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
Katja K H AbenDepartment for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
Antoine G van der HeijdenDepartment of Urology, Radboud University Medical Center, Nijmegen, The Netherlands.
J Alfred WitjesDepartment of Urology, Radboud University Medical Center, Nijmegen, The Netherlands.
Lambertus A L M KiemeneyDepartment for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
Alina VrielingDepartment for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-8178-2125

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity may be associated with increased risk of recurrence and progression in patients with non-muscle invasive bladder cancer (NMIBC), but evidence is limited and inconsistent. We examined the associations of body mass index (BMI), waist circumference, and waist-to-hip ratio (WHR) with risk of recurrence and progression among patients with NMIBC.

methodsThis prospective study included 1029 patients diagnosed with primary NMIBC between 2014 and 2017. Patients reported weight 2 years before diagnosis at baseline, and weight, waist and hip circumference at 3 months postdiagnosis. Associations were quantified using Cox proportional hazard analyses, adjusted for clinical and lifestyle characteristics.

resultsMore than half of patients were overweight (49%) or obese (19%) after diagnosis. During a median follow-up time of 3.6 years, 371 patients developed ≥1 recurrence and 53 experienced progression. No associations with recurrence were observed for BMI (HR

conclusionGeneral and abdominal obesity were not associated with recurrence risk among patients with NMIBC, but might be associated with increased risk of progression. Studies with sufficient sample size to stratify by tumor stage and treatment are needed to better understand whether and how obesity could influence prognosis.

Indexed as

Non-Muscle Invasive Bladder NeoplasmsUrinary Bladder NeoplasmsBody Mass IndexHumansObesityProspective StudiesRisk FactorsWaist Circumferenceabdominalnon-muscle invasive bladder cancerobesityprogressionrecurrence

Identifiers

PMID37800635
PMCPMC10652337

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