Evidence map›Paper›PMID 37800602›Full record

ArticleMolecular medicine reports2023

Tanshinone ⅡA participates in the treatment of endometriosis by regulating adhesion, invasion, angiogenesis and inhibition of PI3K/Akt/mTOR signaling pathway.

Xiaoxiao Zhang, Shumiao Li, Zhenzhen Chen, Wei Liang, Shuting Pei, Feiyue Gou, Zhicheng Jia, Zhaoyang Geng, Xin Gong

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  4. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Xiaoxiao ZhangThe Second Clinical School of Medicine, Beijing University of Chinese Medicine, Beijing 100029, P.R. China.
Shumiao LiThe Second Clinical School of Medicine, Beijing University of Chinese Medicine, Beijing 100029, P.R. China.
Zhenzhen ChenBeijing Key Lab of TCM Collateral Disease Theory Research, School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, P.R. China.
Wei LiangThe Second Clinical School of Medicine, Beijing University of Chinese Medicine, Beijing 100029, P.R. China.
Shuting PeiThe Second Clinical School of Medicine, Beijing University of Chinese Medicine, Beijing 100029, P.R. China.
Feiyue GouThe Second Clinical School of Medicine, Beijing University of Chinese Medicine, Beijing 100029, P.R. China.
Zhicheng JiaAffiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250013, P.R. China.
Zhaoyang GengDepartment of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, P.R. China.
Xin GongDepartment of Gynecology, Dong Fang Hospital of Beijing University of Chinese Medicine, Beijing 100078, P.R. China.
Beijing University of Chinese Medicine · CNAffiliated Hospital of Shandong University of Traditional Chinese Medicine · CNCapital Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis (EMs) is a common gynecological disorder characterized by abnormal growth of the endometrial stroma and glands outside the uterus. Tanshinone IIA, the active component of Chinese medicine Danshen (

Indexed as

EndometriosisProto-Oncogene Proteins c-aktAbietanesAnimalsFemaleHumansIntercellular Adhesion Molecule-1Matrix Metalloproteinase 9Phosphatidylinositol 3-KinasesRatsRats, Sprague-DawleySignal TransductionTOR Serine-Threonine KinasesVascular Endothelial Growth Factor AAbietanesIntercellular Adhesion Molecule-1Matrix Metalloproteinase 9mTOR protein, ratPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-akttanshinoneTOR Serine-Threonine KinasesVascular Endothelial Growth Factor AadhesionendometriosisinvasionNetwork pharmacologyPI3K/Akt/mTOR signaling pathwaytanshinone IIA

Identifiers

PMID37800602
PMCPMC10568248
OpenAlexW4387169896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.