Evidence map›Paper›PMID 37800322›Full record

ArticleHypertension (Dallas, Tex. : 1979)2023

Sleep Variability, Sleep Irregularity, and Nighttime Blood Pressure Dipping.

Yanyan Xu, Vernon A Barnes, Ryan A Harris, Michelle Altvater, Celestine Williams, Kimberly Norland, Jacob Looney, Reva Crandall, Shaoyong Su, Xiaoling Wang

Open access · greenAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Sleep in myalgic encephalomyelitis/chronic fatigue syndrome shows marked night-to-night fluctuation under free-living conditions-results from a matched case-control study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
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  13. Sleep and hypertension - up to date 2024.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yanyan XuGeorgia Prevention Institute (Y.X., V.A.B., R.A.H., M.A., C.W., K.N., J.L., R.C., S.S., X.W.), Medical College of Georgia, Augusta University, GA.
Vernon A BarnesGeorgia Prevention Institute (Y.X., V.A.B., R.A.H., M.A., C.W., K.N., J.L., R.C., S.S., X.W.), Medical College of Georgia, Augusta University, GA.
Ryan A HarrisGeorgia Prevention Institute (Y.X., V.A.B., R.A.H., M.A., C.W., K.N., J.L., R.C., S.S., X.W.), Medical College of Georgia, Augusta University, GA.ORCID 0000-0002-8826-681X
Michelle AltvaterGeorgia Prevention Institute (Y.X., V.A.B., R.A.H., M.A., C.W., K.N., J.L., R.C., S.S., X.W.), Medical College of Georgia, Augusta University, GA.ORCID 0009-0001-4291-6792
Celestine WilliamsGeorgia Prevention Institute (Y.X., V.A.B., R.A.H., M.A., C.W., K.N., J.L., R.C., S.S., X.W.), Medical College of Georgia, Augusta University, GA.
Kimberly NorlandGeorgia Prevention Institute (Y.X., V.A.B., R.A.H., M.A., C.W., K.N., J.L., R.C., S.S., X.W.), Medical College of Georgia, Augusta University, GA.
Jacob LooneyGeorgia Prevention Institute (Y.X., V.A.B., R.A.H., M.A., C.W., K.N., J.L., R.C., S.S., X.W.), Medical College of Georgia, Augusta University, GA.
Reva CrandallGeorgia Prevention Institute (Y.X., V.A.B., R.A.H., M.A., C.W., K.N., J.L., R.C., S.S., X.W.), Medical College of Georgia, Augusta University, GA.ORCID 0000-0001-7002-3273
Shaoyong SuGeorgia Prevention Institute (Y.X., V.A.B., R.A.H., M.A., C.W., K.N., J.L., R.C., S.S., X.W.), Medical College of Georgia, Augusta University, GA.ORCID 0000-0002-6059-2760
Xiaoling WangGeorgia Prevention Institute (Y.X., V.A.B., R.A.H., M.A., C.W., K.N., J.L., R.C., S.S., X.W.), Medical College of Georgia, Augusta University, GA.ORCID 0000-0001-9290-7926
Augusta University · US

Funding

Role of Skeletal Muscle Health on Poor LIfestyle Related Type 2 Diabetes and Cardiovascular Disease RiskR01DK117365 · NIDDK · AUGUSTA UNIVERSITY · PI HARRIS, RYAN A, WANG, XIAOLING · 2018 to 2022
$3.3M
Psychosocial stress, epigenetics and health disparity in hypertensionR01MD013307 · NIMHD · AUGUSTA UNIVERSITY · PI SU, SHAOYONG · 2019 to 2023
$3.0M
Pediatric Ambulatory Blood Pressure Trajectory and Brain Health in MidlifeR01HL143440 · NHLBI · AUGUSTA UNIVERSITY · PI MCDOWELL, JENNIFER E, SU, SHAOYONG · 2019 to 2022
$2.8M
NHLBI NIH HHS R01 HL143440NIDDK NIH HHS R01 DK117365NIMHD NIH HHS R01 MD013307
6 · The paper itself

Abstract

backgroundCircadian rhythm regulates many important biological functions in humans. The goal of this study is to explore the impact of day-to-day deviations in the sleep-wake cycle on nighttime blood pressure (BP) dipping and further examine whether the ethnic difference in day-to-day deviations in sleep patterns can explain the ethnic difference in nighttime BP dipping.

methodsTwenty-four-hour ambulatory BP monitoring and 7-day accelerometer data were obtained from 365 adult participants (age range, 18.7-50.1 years; 52.6% Black participants and 47.3% European Americans; 64.1% females). Systolic BP dipping level was used to represent nighttime BP dipping. The SD of sleep duration was calculated as the index of sleep variability, and the SD of sleep midpoint was calculated as the index of sleep irregularity.

resultsA 1-hour increase in the SD of sleep midpoint was associated with a 1.16% decrease in nighttime BP dipping (

conclusionsSleep variability and sleep irregularity are associated with blunted BP dipping in the general population. In addition, data from the present investigation also demonstrate that the ethnic difference in sleep irregularity could partly explain the ethnic difference in BP dipping, an important finding that may help reduce the health disparity between Black participants and European Americans.

Indexed as

HypertensionSleepAdolescentAdultBlack or African AmericanBlood PressureBlood Pressure Monitoring, AmbulatoryCircadian RhythmFemaleHumansMaleMiddle AgedWhiteYoung Adultblood pressuredippingnighttimesleep irregularitysleep variability

Identifiers

PMID37800322
PMCPMC10873041
OpenAlexW4387393070

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.