Evidence map›Paper›PMID 37799795›Full record

ArticleJournal of arrhythmia2023

Predictors of implantation failure in left bundle branch area pacing using a lumenless lead in patients with bradycardia.

Hiroyuki Kato, Toshiaki Sato, Kenji Shimeno, Shinji Mito, Taku Nishida, Kyoko Soejima

Open access · goldAbstract read
In one paragraph

Article in Journal of arrhythmia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Left bundle branch area pacing in patients with and without interventricular septal hypertrophy: a systemic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Pooled it
  2. Pooled it
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  4. Clinical Prediction Model for Unsuccessful Left Bundle Branch Area Pacing.Journal of cardiovascular electrophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Hiroyuki KatoDepartment of Cardiology, Japan Community Healthcare Organization Chukyo Hospital Nagoya Japan.
Toshiaki SatoDivision of Advanced Arrhythmia Management Kyorin University School of Medicine Mitaka Japan.ORCID https://orcid.org/0000-0002-0073-3592
Kenji ShimenoDepartment of Cardiology, Osaka City General Hospital Osaka Japan.
Shinji MitoDepartment of Cardiology, Chikamori Hospital Kochi Japan.
Taku NishidaDepartment of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Kyoko SoejimaDepartment of Cardiovascular Medicine Kyorin University School of Medicine Mitaka Japan.
Kyorin University · JPChikamori Hospital · JPJapan Community Healthcare Organization · JPNara Medical University · JPOsaka City General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Left bundle branch area pacing (LBBAP) is a novel conduction system pacing technique. In this multicenter study, we aimed to evaluate the procedural success, safety, and preoperative predictors of procedural failure of LBBAP. Methods: LBBAP was attempted in 285 patients with pacemaker indications for bradyarrhythmia, which were mainly atrioventricular block (AVB) (68.1%) and sick sinus syndrome (26.7%). Procedural success and electrophysiological and echocardiographic parameters were evaluated. Results: LBBAP was successful in 247 (86.7%) patients. Left bundle branch (LBB) capture was confirmed in 54.7% of the population. The primary reasons for procedural failure were the inability of the pacemaker lead to penetrate deep into the septum (76.3%) and failure to achieve shortening of stimulus to left ventricular (LV) activation time in lead V6 (18.4%). Thickened interventricular septum (odds ratio [OR], 2.48; 95% confidence interval [CI], 1.15-5.35), severe tricuspid regurgitation (OR, 8.84; 95% CI, 1.22-64.06), and intraventricular conduction delay (OR, 8.16; 95% CI, 2.32-28.75) were preoperative predictors of procedural failure. The capture threshold and ventricular amplitude remained stable, and no major complications occurred throughout the 2-year follow-up. In patients with ventricular pacing burden >40%, the LV ejection fraction remained high regardless of LBB capture. Conclusions: Successful LBBAP was affected by abnormal cardiac anatomy and intraventricular conduction. LBBAP is feasible and safe as a primary strategy for patients with AVB, depending on ventricular pacing.

Indexed as

bradyarrhythmiaconduction system pacingleft bundle branch area pacingleft bundle branch pacingleft ventricular septal pacing

Identifiers

PMID37799795
PMCPMC10549844
OpenAlexW4385582659

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.