ArticleThe Annals of the American Academy of Political and Social Science2022
The Effects of Opioid Use during Pregnancy on Infant Health and Well-Being.
Article in The Annals of the American Academy of Political and Social Science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Referral linkages to support pregnant and postpartum individuals with opioid use disorders in Florida: a social network analysis.Addiction science & clinical practice · 2026Article
- Association between prenatal opioid exposure and health, education, and foster care between ages 0 and 18.PNAS nexus · 2026Article
- Prenatal opioid use disorder and child protective service involvement: Does consistent treatment matter?Journal of substance use and addiction treatment · 2025Article
- Prenatal opioid exposure, neonatal abstinence syndrome diagnosis, and child welfare involvement.Child abuse & neglect · 2025Article
- Trends in prenatal prescription opioid use among Medicaid beneficiaries in Wisconsin, 2010-2019.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Prenatal opioid exposure by likelihood of exposure and risk to prenatal development: Medicaid-covered births in Wisconsin, 2010-2019.Science advances · 2024Article
- Distinct Trajectories of Prescription Opioid Exposure in Pregnancy and Risk of Adverse Birth Outcomes.Journal of addiction medicineArticle
- Importance of Modifiable Factors to Infant Health in the Context of Prenatal Opioid Use Disorder.Journal of addiction medicineObservational
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
In this study, we estimate the first causal effects of in utero opioid exposure on infant health at birth and child protective services reports. We employ maternal fixed-effects models using linked administrative data capturing 259,723 infants born to 176,224 mothers enrolled in Medicaid between 2010 and 2019. Our preferred specifications suggest that neonatal abstinence syndrome and NICU admission bear strong associations with prenatal opioid exposure, concentrated on illicit and medication assisted treatment (MAT) exposure in the first and third trimesters. We find that prenatal opioid exposure is associated with increased CPS reports, low birth weight, preterm birth, and small for gestational age, though these measures are less sensitive with respect to the timing of exposure. While we detect relatively smaller effects of non-MAT prescription opioid exposure on NAS, NICU admission, low birthweight, these effects are not trivial, suggesting that medical professionals should consider balancing the potential for adverse side effects of infants with the benefits of pain management for pregnant women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.