ArticleJournal of clinical and experimental dentistry2023
Raman microscopy evaluation of the preventive effect of a modified orthodontic adhesive with silver nanoparticles on the formation of white spot lesions.
Article in Journal of clinical and experimental dentistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
- Antimicrobial efficacy and bonding properties of orthodontic bonding systems enhanced with silver nanoparticles: a systematic review with meta-analysis.BMC oral health · 2024Pooled it
- Usage of Silver Nanoparticles in Orthodontic Bonding Reagents.Journal of functional biomaterials · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Silver nanoparticles (AgNPs) are an effective antibacterial agent, and their inclusion in orthodontic adhesives has been proposed to prevent white spot lesions (WSLs). The objective of this study was to evaluate by Raman microscopy the preventive effect of an orthodontic adhesive modified with AgNPs on the formation of WSLs. Material and Methods: AgNPs were added in four concentrations (0.05%, 0.1%, 0.5%, and 1%) to an orthodontic adhesive. Metal brackets were bonded with the experimental adhesives, and the specimens were subjected to a microbial model for caries induction. The preventive effect on the formation of WSLs was evaluated by Raman microscopy, considering the intensity peak of the phosphate ion at 960 cm-1. The acquisition mode was linear scanning in the most representative lesion area, with a length of 136µm. Intensity values expressed the relative amount of phosphate ions remaining in the lesion. Microphotographs were analyzed in the Image J program to assess the depth of the lesions. Results: Significant differences were observed between all groups ( Conclusions: AgNPs were effective in decreasing the formation of WSLs. At a higher concentration of AgNPs, a more significant preventive effect on the formation of WSLs results in a relative amount of phosphate ion close to sound enamel values.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.