Evidence map›Paper›PMID 37799680›Full record

ArticleBiomedical optics express2023

Visible-light optical coherence tomography platform for the characterization of the skin barrier.

Dmitry G Revin, Robert A Byers, Meng Q Duan, Wei Li, Stephen J Matcher

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dmitry G RevinDepartment of Electronic and Electrical Engineering, University of Sheffield, Sir Frederick Mappin Building, Sheffield, S1 3JD, UK.
Robert A ByersDermatology Research, Department of Infection and Immunity and Cardiovascular Disease, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.ORCID https://orcid.org/0000-0001-8582-9325
Meng Q DuanDepartment of Electronic and Electrical Engineering, University of Sheffield, Sir Frederick Mappin Building, Sheffield, S1 3JD, UK.
Wei LiDepartment of Electronic and Electrical Engineering, University of Sheffield, Sir Frederick Mappin Building, Sheffield, S1 3JD, UK.
Stephen J MatcherDepartment of Electronic and Electrical Engineering, University of Sheffield, Sir Frederick Mappin Building, Sheffield, S1 3JD, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We demonstrate a free-space, trolley-mountable Fourier domain visible-light optical coherence tomography (OCT) system for studying the stratum corneum in non-palmar human skin. An axial resolution of 1 µm in tissue and at least -75 dB sensitivity have been achieved. High-quality B-scans, containing 1600 A-scans, are acquired at a rate of 39 Hz. Images from the dorsal hand, ventral wrist and ventral forearm areas are obtained, with a clearly resolved stratum corneum layer (typically 5-15 µm thick) presenting as a hypoechogenic dark layer below the bright entrance signal, similar to that found in palmar skin with traditional OCT systems. We find that the appearance of the stratum corneum layer strongly depends on its water content, becoming brighter after occlusive hydration.

Identifiers

PMID37799680
PMCPMC10549730

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.