Evidence map›Paper›PMID 37799586›Full record

ArticleRSC chemical biology2023

RiPP enzyme heterocomplex structure-guided discovery of a bacterial borosin α-

K K Crone, T Jomori, F S Miller, J A Gralnick, M H Elias, M F Freeman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

K K CroneDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota - Twin Cities St. Paul 55108 USA mffreema@umn.edu.ORCID https://orcid.org/0000-0001-9888-4710
T JomoriThe BioTechnology Institute, University of Minnesota - Twin Cities St. Paul 55108 USA.
F S MillerDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota - Twin Cities St. Paul 55108 USA mffreema@umn.edu.ORCID https://orcid.org/0000-0002-6948-3683
J A GralnickThe BioTechnology Institute, University of Minnesota - Twin Cities St. Paul 55108 USA.
M H EliasDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota - Twin Cities St. Paul 55108 USA mffreema@umn.edu.
M F FreemanDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota - Twin Cities St. Paul 55108 USA mffreema@umn.edu.ORCID https://orcid.org/0000-0002-0491-9618
University of Minnesota · USBiotechnology Institute · US

Funding

Discovery and characterization of biocatalysts for ribosomally encoded alpha-N-methylated peptide natural productsR35GM133475 · NIGMS · UNIVERSITY OF MINNESOTA · PI Michael F Freeman · 2019 to 2026
$2.7M
NIGMS NIH HHS R35 GM133475
6 · The paper itself

Abstract

Amide peptide backbone methylation is a characteristic post-translational modification found in a family of ribosomally synthesized and post-translationally modified peptide natural products (RiPPs) called borosins. Previously, we bioinformatically identified >1500 putative borosin pathways in bacteria; however, none of the pathways were associated with a known secondary metabolite. Through in-depth characterization of a borosin pathway in

Identifiers

PMID37799586
PMCPMC10549244
OpenAlexW4386038515

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.