Evidence map›Paper›PMID 37799174›Full record

ArticleBeilstein journal of organic chemistry2023

Synthesis and biological evaluation of

Jessica Villegas, Bryce C Ball, Katelyn M Shouse, Caleb W VanArragon, Ashley N Wasserman, Hannah E Bhakta, Allen G Oliver, Danielle A Orozco-Nunnelly, Jeffrey M Pruet

Abstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jessica VillegasDepartment of Chemistry, Valparaiso University, 1710 Chapel Dr, Valparaiso, IN 46383, USA.ORCID https://orcid.org/0000-0003-0268-5114
Bryce C BallDepartment of Chemistry, Valparaiso University, 1710 Chapel Dr, Valparaiso, IN 46383, USA.
Katelyn M ShouseDepartment of Biology, Valparaiso University, 1610 Campus Dr, Valparaiso, IN 46383, USA.ORCID https://orcid.org/0000-0003-2032-9391
Caleb W VanArragonDepartment of Biology, Valparaiso University, 1610 Campus Dr, Valparaiso, IN 46383, USA.
Ashley N WassermanIvy Tech Community College, 410 E Columbus Dr, East Chicago, IN 46312, USA.
Hannah E BhaktaDepartment of Chemistry, Valparaiso University, 1710 Chapel Dr, Valparaiso, IN 46383, USA.
Allen G OliverDepartment of Chemistry and Biochemistry, University of Notre Dame, 251 Nieuwland Hall, Notre Dame, IN 46556, USA.
Danielle A Orozco-NunnellyDepartment of Biology, Valparaiso University, 1610 Campus Dr, Valparaiso, IN 46383, USA.ORCID https://orcid.org/0000-0003-3381-0504
Jeffrey M PruetDepartment of Chemistry, Valparaiso University, 1710 Chapel Dr, Valparaiso, IN 46383, USA.ORCID https://orcid.org/0000-0002-6100-4633

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the lack of new antimicrobial drug discovery in recent years and an ever-growing prevalence of multidrug-resistant "superbugs", there is a pressing need to explore alternative ways to combat pathogenic bacterial and fungal infections. Building upon our previous work in the field of medicinal phytochemistry, the present study is focused on designing, synthesizing, and testing the altered bioactivity of new variants of two original bioactive molecules found in the

Indexed as

benzylisoquinolineberberinechelerythrinedrug discoveryplant-derived antimicrobials

Identifiers

PMID37799174
PMCPMC10548253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.