ArticleNeurospine2023
Proximal Junctional Failure in Adult Spinal Deformity Surgery: An In-depth Review.
Article in Neurospine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Association between lumbar lordosis and proximal junctional failure following adult spinal deformity surgery: a systematic review and meta-analysis.Spine deformity · 2026Pooled it
- Machine learning-based prediction of proximal junctional pathology after adult spinal deformity surgery: a systematic review and diagnostic test accuracy meta-analysis.Acta neurochirurgica · 2026Pooled it
- The use of hooks in upper instrumented vertebra to prevent proximal junctional complications: a systematic review and meta-analysis.BMC surgery · 2026Pooled it
- Risk Factors for Proximal Junctional Kyphosis in Osteoporotic Versus Non-Osteoporotic Patients After Adult Spinal Deformity Surgery.Journal of clinical medicine · 2026Article
- Association of Perioperative Teriparatide Use with Postoperative Complications in Spinal Fusion Surgery: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Hybrid Posterior Fixation Incorporating Cervical Facet Fixation for the Treatment of Proximal Junctional Failure.Journal of orthopaedic case reports · 2026Article
- Neurologic deficits due to proximal junctional kyphosis after adult spinal deformity surgery: how often do they happen and do they improve?Spine deformity · 2026Article
- Article
- Acute Disc Herniation at the Proximal Junctional Segment (UIV/UIV + 1) Following Long Segment Spinal Fusion With Cement-Augmented Instrumentation: A Retrospective Study.International journal of spine surgery · 2026Article
- Role of paraspinal muscle fatty infiltration in predicting adjacent segment disease after lumbar spinal fusion: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- A predictable cascade of junctional failure following progressive long-segment fusion: an 11-year case analysis.Journal of surgical case reports · 2026Article
- Preoperative Thoracolumbar Mobility (ΔTLK) Predicts Early Upper Instrumented Vertebra-Adjacent Fracture after Lower Thoracic-Pelvic Fusion in Elderly Patients with Adult Spinal Deformity.Spine surgery and related research · 2026Article
- Comparison of Hook Fixation and Vertebroplasty for Prevention of Proximal Junctional Failure: A Retrospective Cohort Study.Global spine journal · 2026Article
- Superior displacement of the inflexion point does not predict proximal junctional kyphosis after fusion for adult spinal deformity.Journal of spine surgery (Hong Kong) · 2026Article
- Fusion strategy after odontoid fracture and three-column atlantoaxial displacement in a patient with prior C2-pelvis fusion: a case report.Journal of spine surgery (Hong Kong) · 2025Article
- Evaluation of Bone Mineral Density: Correlating MRI Cervical Vertebral Bone Quality, CT Hounsfield Units, and DEXA T-Scores.Medical sciences (Basel, Switzerland) · 2025Article
- Article
- Predicting proximal junctional failure in adult spinal deformity patients using machine learning models based on spinal alignment parameters.Scientific reports · 2025Article
- [Radiological imaging of spinal trauma in special situations].Radiologie (Heidelberg, Germany) · 2025Review
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adult spinal deformity (ASD) surgery aims to correct abnormal spinal curvature in adults, leading to improved functionality and reduced pain. However, this surgery is associated with various complications, one of which is proximal junctional failure (PJF). PJF can have a significant impact on a patient's quality of life, necessitating a comprehensive understanding of its causes and the development of effective management strategies. This review aims to provide an in-depth understanding of PJF in ASD surgery. PJF is a complex complication resulting from a multitude of factors including patient characteristics, surgical techniques, and postoperative management. Age, osteoporosis, overcorrection of sagittal alignment, and poor bone quality are identified as significant risk factors. The clinical implications of PJF are substantial, often requiring revision surgery and causing a considerable decrease in patients' quality of life. Prevention strategies include careful preoperative planning, appropriate patient selection, and optimization of surgical techniques. Treatment often necessitates a multifaceted approach, including surgical intervention and the management of underlying risk factors. Predictive modeling is an emerging field that may offer a promising avenue for the risk stratification of patients and individualized preventive strategies. A thorough understanding of PJF's pathogenesis, risk factors, and clinical implications is essential for surgeons involved in ASD surgery. Current preventive measures and treatment strategies aim to mitigate the risk and manage the complications of PJF, but the complication cannot be entirely prevented. Future research should focus on the development of more effective preventive and treatment strategies, and predictive models could be valuable in this pursuit.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.