Evidence map›Paper›PMID 37798356›Full record

ArticleNature chemical biology2023

Endogenous currents in HEK 293 cells are inhibited by memantine.

Neil L Harrison, Geoffrey W Abbott, Conor McClenaghan, Colin G Nichols, David Cabrera-Garcia

Abstract readLetterComment
PubMed Publisher
In one paragraph

Article in Nature chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Deep Learning-Based Ion Channel Kinetics Analysis for Automated Patch Clamp Recording.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Neil L HarrisonDepartment of Anesthesiology, Columbia University, New York, NY, USA. nh2298@columbia.edu.ORCID 0000-0002-8013-7765
Geoffrey W AbbottDepartment of Physiology and Biophysics, University of California at Irvine, Irvine, CA, USA.ORCID 0000-0003-4552-496X
Conor McClenaghanCenter for Advanced Biotechnology and Medicine and Departments of Pharmacology and Medicine, Robert Wood Johnson School of Medicine, Rutgers University, Piscataway, NJ, USA.
Colin G NicholsCenter for the Investigation of Membrane Excitability Diseases, and Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-4929-2134
David Cabrera-GarciaNetherlands Institute for Neuroscience, Amsterdam, the Netherlands.ORCID 0000-0001-9609-9102
Columbia University Irving Medical Center · USNetherlands Institute for Neuroscience · NLRutgers, The State University of New Jersey · USUniversity of California, Irvine · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MemantineReceptors, N-Methyl-D-AspartateHEK293 CellsHumansMemantineReceptors, N-Methyl-D-Aspartate

Identifiers

PMID37798356
OpenAlexW4387363959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.