Evidence map›Paper›PMID 37798265›Full record

ArticleNature communications2023

Viral kinetics of sequential SARS-CoV-2 infections.

Stephen M Kissler, James A Hay, Joseph R Fauver, Christina Mack, Caroline G Tai, Deverick J Anderson, David D Ho, Nathan D Grubaugh, Yonatan H Grad

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Final-Size Solutions for SIRI Models with Vaccination.Bulletin of mathematical biology · 2026
    Article
  4. Article
  5. Article
  6. Inferring transmission risk of respiratory viral infection from the viral load kinetics of SARS-CoV-2, England, 2020 to 2021 and influenza A virus, Hong Kong, 2008 to 2012.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Timing and Predictors of Loss of Infectivity Among Healthcare Workers With Mild Primary and Recurrent COVID-19: A Prospective Observational Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Observational
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Stephen M KisslerDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID http://orcid.org/0000-0001-6000-8387
James A HayBig Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-1998-1844
Joseph R FauverDepartment of Epidemiology, University of Nebraska Medical Center, Omaha, NE, USA.
Christina MackIQVIA, Durham, NC, USA.
Caroline G TaiIQVIA, Durham, NC, USA.
Deverick J AndersonDuke Center for Antimicrobial Stewardship and Infection Prevention, Durham, NC, USA.
David D HoVagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.ORCID http://orcid.org/0000-0003-1627-149X
Nathan D GrubaughDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Yonatan H GradDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. ygrad@hsph.harvard.edu.ORCID http://orcid.org/0000-0001-5646-1314
Harvard University · USIQVIA (United States) · USColumbia University · USDuke University · USUniversity of Nebraska Medical Center · USUniversity of Oxford · GBYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Epidemiology of Infectious Diseases and BiodefenseT32AI007535 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI GRAD, YONATAN H, MURRAY, MEGAN B · 1998 to 2025
$4.8M
High Performance Computing Instrumentation for the Yale Center for Genome AnalysisS10OD030363 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2022 to 2022
$1.2M
CDC HHS 200-2016-91779NCATS NIH HHS UL1 TR001863NIAID NIH HHS T32 AI007535NIH HHS S10 OD030363
6 · The paper itself

Abstract

The impact of a prior SARS-CoV-2 infection on the progression of subsequent infections has been unclear. Using a convenience sample of 94,812 longitudinal RT-qPCR measurements from anterior nares and oropharyngeal swabs, we identified 71 individuals with two well-sampled SARS-CoV-2 infections between March 11

Indexed as

COVID-19COVID-19 TestingHumansKineticsResearch DesignSARS-CoV-2

Identifiers

PMID37798265
PMCPMC10556125
OpenAlexW4387372424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.