Evidence map›Paper›PMID 37798236›Full record

ArticleNutrition, metabolism, and cardiovascular diseases : NMCD2023

Associations between avocado intake and measures of glucose and insulin homeostasis in Hispanic individuals with and without type 2 diabetes: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

MacKenzie K Senn, Mark O Goodarzi, Gautam Ramesh, Matthew A Allison, Mariaelisa Graff, Kristin L Young, Gregory A Talavera, Amanda C McClain, Tanya P Garcia, Jerome I Rotter and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Nutrition, metabolism, and cardiovascular diseases : NMCD, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

MacKenzie K SennUSDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, 1100 Bates Avenue Houston, TX 77030, USA; The University of Texas Health Science Center at Houston School of Public Health, 1200 Pressler Street, Houston, TX 77030, USA.
Mark O GoodarziDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Gautam RameshSchool of Medicine, University of California, La Jolla, San Diego, CA 92037, USA.
Matthew A AllisonDivision of Preventive Medicine, Department of Family Medicine, University of California, La Jolla, San Diego, CA 92037, USA.
Mariaelisa GraffDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599, USA.
Kristin L YoungDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599, USA.
Gregory A TalaveraDepartment of Psychology, San Diego State University, San Diego, CA 92182, USA.
Amanda C McClainSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA 92182, USA.
Tanya P GarciaDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599, USA.
Jerome I RotterThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Alexis C WoodUSDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, 1100 Bates Avenue Houston, TX 77030, USA. Electronic address: LekkiWood@Gmail.com.
University of North Carolina at Chapel Hill · USChildren's Nutrition Research Center at Baylor College of Medicine · USSan Diego State University · USUniversity of California San Diego · USCedars-Sinai Medical Center · USUCLA Medical Center · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrea L Hevener · 2003 to 2026
$40.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Impact of the gut microbiome and diet on change in insulin homeostasis and cardiometabolic riskR01DK109588 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI GOODARZI, MARK, PETROSINO, JOSEPH FRANK · 2017 to 2021
$3.1M
Thalassemia Clinical Research Network, CanadaU01HL065233 · NHLBI · UNIVERSITY HEALTH NETWORK · PI OLIVIERI, NANCY F · 2000 to 2009
$2.6M
GENETIC ARCHITECTURE OF PLASMA T-PA AND PAI-1R01HL065234 · NHLBI · VANDERBILT UNIVERSITY · PI MOORE, JASON H. · 2000 to 2004
$1.7M
Capacity-oriented approaches to food security, diet quality, and cardiovascular disease risk among Hispanics/LatinosK01HL150406 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI MCCLAIN, AMANDA CHRISTINE · 2020 to 2024
$915k
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
NCATS NIH HHS UL1 TR001420NCATS NIH HHS UL1 TR001881NHGRI NIH HHS HHSN268201300003CNHLBI NIH HHS HHSN268201300003INHLBI NIH HHS K01 HL150406NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NIDDK NIH HHS P30 DK063491NIDDK NIH HHS P30 DK111022NIDDK NIH HHS R01 DK109588
6 · The paper itself

Abstract

BACKGROUND AND

aimsTo investigate associations between avocado intake and glycemia in adults with Hispanic/Latino ancestry. METHODS AND

resultsThe associations of avocado intake with measures of insulin and glucose homeostasis were evaluated in a cross-sectional analysis of up to 14,591 Hispanic/Latino adults, using measures of: average glucose levels (hemoglobin A1c; HbA1c), fasting glucose and insulin, glucose and insulin levels after an oral glucose tolerance test (OGTT), and calculated measures of insulin resistance (HOMA-IR, and HOMA-%β), and insulinogenic index. Associations were assessed using multivariable linear regression models, which controlled for sociodemographic factors and health behaviors, and which were stratified by dysglycemia status. In those with normoglycemia, avocado intake was associated with a higher insulinogenic index (β = 0.17 ± 0.07, P = 0.02). In those with T2D (treated and untreated), avocado intake was associated with lower hemoglobin A1c (HbA1c; β = -0.36 ± 0.21, P = 0.02), and lower fasting glucose (β = -0.27 ± 0.12, P = 0.02). In the those with untreated T2D, avocado intake was additionally associated with HOMA-%β (β = 0.39 ± 0.19, P = 0.04), higher insulin values 2-h after an oral glucose load (β = 0.62 ± 0.23, P = 0.01), and a higher insulinogenic index (β = 0.42 ± 0.18, P = 0.02). No associations were observed in participants with prediabetes.

conclusionsWe observed an association of avocado intake with better glucose/insulin homeostasis, especially in those with T2D.

Indexed as

Diabetes Mellitus, Type 2DietInsulin ResistancePerseaAdultBlood GlucoseCross-Sectional StudiesGlucoseGlycated HemoglobinHispanic or LatinoHomeostasisHumansInsulinPublic HealthBlood GlucoseGlucoseGlycated HemoglobinInsulinAvocadoDietHbA1cInsulin homeostasisPostprandialType 2 diabetes

Identifiers

PMID37798236
PMCPMC10842938
OpenAlexW4385988690

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.