Evidence map›Paper›PMID 37797713›Full record

ArticleInsect biochemistry and molecular biology2023

Pyruvate kinase is post-translationally regulated by sirtuin 2 in Aedes aegypti mosquitoes.

Natthida Petchampai, Jun Isoe, Prashanth Balaraman, Max Oscherwitz, Brendan H Carter, Cecilia G Sánchez, Patricia Y Scaraffia

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Insect biochemistry and molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Natthida PetchampaiDepartment of Tropical Medicine and Infectious Disease, Vector-Borne Infectious Disease Research Center, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, 70112, USA.
Jun IsoeDepartment of Entomology, The University of Arizona, Tucson, AZ, 85721, USA.
Prashanth BalaramanDepartment of Tropical Medicine and Infectious Disease, Vector-Borne Infectious Disease Research Center, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, 70112, USA.
Max OscherwitzDepartment of Entomology, The University of Arizona, Tucson, AZ, 85721, USA.
Brendan H CarterDepartment of Tropical Medicine and Infectious Disease, Vector-Borne Infectious Disease Research Center, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, 70112, USA.
Cecilia G SánchezDepartment of Tropical Medicine and Infectious Disease, Vector-Borne Infectious Disease Research Center, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, 70112, USA.
Patricia Y ScaraffiaDepartment of Tropical Medicine and Infectious Disease, Vector-Borne Infectious Disease Research Center, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, 70112, USA. Electronic address: pscaraff@tulane.edu.
Tulane University · USUniversity of Arizona · US

Funding

Mechanistic regulation of ammonia metabolism in Aedes aegypti mosquitoesR01AI146199 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI SCARAFFIA, PATRICIA YOLANDA · 2019 to 2024
$1.9M
NIAID NIH HHS R01 AI146199
6 · The paper itself

Abstract

We previously demonstrated that Aedes aegypti pyruvate kinase (AaPK) plays a key role in the regulation of both carbon and nitrogen metabolism in mosquitoes. To further elucidate whether AaPK can be post-translationally regulated by Ae. aegypti sirtuin 2 (AaSirt2), an NAD

Indexed as

AedesAnimalsFemaleLysinePyruvate KinaseRNA InterferenceSirtuin 2LysinePyruvate KinaseSirtuin 2Enzyme regulationGlucose and ammonia metabolismLysine acetylationPost-translational modificationProtein deacetylationStarvation

Identifiers

PMID37797713
PMCPMC10698509
OpenAlexW4387336342

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.