ReviewPsychiatry research2023
Building a neurobiological framework to elucidate neural mechanisms, aid early risk detection, and develop new treatments for Bipolar Disorder.
Review in Psychiatry research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Diagnostic and sex effects on frontostriatal brain wiring structural organization in early psychosis affective subjects compared to healthy controls.Molecular psychiatry · 2026Article
- High Beta Power in the Ventrolateral Prefrontal Cortex Indexes Human Approach Behavior: A Case Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Neuronal Synaptic Communication and Mitochondrial Energetics in Human Health and Disease.Advances in experimental medicine and biology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
This article describes the progress that my colleagues and I have made over the last two decades in building a clinical neuroscience research program in Bipolar Disorder (BD). Here, we have focused on key research themes to ultimately help with early risk detection and the development of better treatments for individuals with BD. We have described the main areas that we are pursuing, namely, understanding the underlying neural mechanisms of BD and BD risk, differentiating BD and BD risk from depressive disorder risk, and the development of new treatments for individuals with BD. We conclude with a summary of future directions in our research that include examination of the molecular and metabolic abnormalities associated with neural network abnormalities underlying mania/hypomania risk, testing neural risk markers in independent samples stratified according to familial risk for BD, and the study of early infant and child neurodevelopmental processes that confer risk for affective disorders, including BD, in order to elucidate early neural risk markers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.