Evidence map›Paper›PMID 37797411›Full record

Observational studyJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2023

Racial and ethnic disparities in the usage and outcomes of ischemic stroke treatment in the United States.

Delaney Metcalf, Donglan Zhang

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Racial and Ethnic Disparities in Stroke Incidence and Outcomes.Current cardiovascular risk reports · 2025
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Delaney MetcalfMedical College of Georgia and Augusta University/ University of Georgia Medical Partnership, Athens, GA 30605, United States. Electronic address: dmetcalf@augusta.edu.
Donglan ZhangCenter for Population Health and Health Services, Research Department of Foundations of Medicine, NYU Grossman Long Island School of Medicine, Mineola, NY 11501, United States.
University of Georgia · US

Funding

Using machine learning and causal inference approaches to investigate disparities in Alzheimer’s disease and related dementias outcomesR01MD013886 · NIMHD · UNIVERSITY OF GEORGIA · PI ZHANG, DONGLAN · 2019 to 2022
$2.4M
NIMHD NIH HHS R01 MD013886
6 · The paper itself

Abstract

objectivesThis study explores racial and ethnic differences in 1) receiving tissue plasminogen activator (tPA) and endovascular thrombectomy (EVT) as treatment for ischemic stroke and 2) outcomes and quality of care after use of tPA or EVT in the US. MATERIALS AND

methodsAn observational analysis of 89,035 ischemic stroke patients from the 2019 National Inpatient Sample was conducted. We performed weighted logistic regressions between race and ethnicity and 1) tPA and EVT utilization and 2) in-hospital mortality. We also performed a weighted Poisson regression between race and ethnicity and length of stay (LOS) after tPA or EVT.

resultsNon-Hispanic (NH) Black patients had significantly lower odds of receiving tPA (Adjusted odds ratio [AOR] = 0.85, 95 % Confidence Internal [C.I.]: 0.80-0.91) and EVT (AOR = 0.75, 95 % CI: 0.70-0.82) than NH White patients. Minority populations (including but not limited to NH Black, Hispanic, Pacific Islander, Native American, and Asian) had significantly longer hospital LOS after treatment with tPA or EVT. We did not find a significant difference between race/ethnicity and in-hospital mortality post-tPA or EVT.

conclusionsWhile we failed to find a difference in in-hospital mortality, racial and ethnic disparities are still evident in the decreased usage of tPA and EVT and longer LOSs for racial and ethnic minority patients. This study calls for interventions to expand the utilization of tPA and EVT and advance quality of care post-tPA or EVT in order to improve stroke care for minority patients.

Indexed as

Ischemic StrokeStrokeEthnicityFibrinolytic AgentsHumansMinority GroupsTissue Plasminogen ActivatorUnited StatesFibrinolytic AgentsTissue Plasminogen ActivatorEndovascular thrombectomyIschemic strokeIschemic stroke treatmentRacial and ethnic disparitiesTissue plasminogen activator

Identifiers

PMID37797411
PMCPMC10841526
OpenAlexW4387321224

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.