Evidence map›Paper›PMID 37797060›Full record

ArticlePloS one2023

Physical and psychological recovery after vaginal childbirth with and without epidural analgesia: A prospective cohort study.

Ayumi Maeda, Rimu Suzuki, Rie Maurer, Sumie Kurokawa, Miki Kaneko, Rie Sato, Hiromi Nakajima, Kyoko Ogura, Michiko Yamanaka, Tokujiro Uchida and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Ayumi MaedaDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States of America.ORCID 0000-0002-6919-6465
Rimu SuzukiDepartment of Anesthesia, St. Luke's International Hospital, Tokyo, Japan.
Rie MaurerCenter for Clinical Investigation, Brigham and Women's Hospital, Boston, MA, United States of America.
Sumie KurokawaDepartment of Nursing, St. Luke's International Hospital, Tokyo, Japan.
Miki KanekoDepartment of Nursing, St. Luke's International Hospital, Tokyo, Japan.
Rie SatoDepartment of Nursing, St. Luke's International Hospital, Tokyo, Japan.
Hiromi NakajimaDepartment of Nursing, St. Luke's International Hospital, Tokyo, Japan.
Kyoko OguraDepartment of Nursing, St. Luke's International Hospital, Tokyo, Japan.
Michiko YamanakaDepartment of Integrated Women's Health, Center for Medical Genetics and St. Luke's International Hospital, Tokyo, Japan.
Tokujiro UchidaDepartment of Anesthesiology, Tokyo Medical and Dental University, Tokyo, Japan.ORCID 0000-0002-9474-0020
Yasuko NagasakaDepartment of Anesthesia, Tokyo Women's Medical University, Tokyo, Japan.ORCID 0000-0002-6259-3388
St. Luke's International Hospital · JPBrigham and Women's Hospital · USTokyo Medical and Dental University · JPTokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnhanced recovery is the gold standard in modern perioperative management, including that for cesarean deliveries. However, qualitative and quantitative data on the physical and psychological recovery of women after vaginal childbirth are limited. Whether neuraxial labor analgesia influences postpartum recovery is unknown.

methodsPrimiparous women anticipating a vaginal childbirth between January 2020 and May 2021 were enrolled. Women with major comorbidities or postpartum complications and those who underwent a cesarean delivery were excluded. Daily step count was measured using a wrist-worn activity tracker (FitbitTM Inspire HR) for 120 hours after vaginal childbirth. Subjective fatigue levels and health-related quality of life were assessed using the Multidimensional Fatigue Inventory (MFI) and EuroQol 5 Dimension 5 Level (EQ-5D-5L), respectively, at the 3rd trimester antenatal visit, on postpartum day 1 and 3, and at the one-month postpartum visit. Rest and dynamic pain scores and the location of pain were documented by participants during postpartum hospitalization.

resultsAmong 300 women who were enrolled antenatally, 95 and 116 had a vaginal delivery without (NCB group) and with (EPL group) epidural analgesia, respectively. The median number of steps per 24 hours increased daily in both groups, and no significant difference was detected between the groups. Postpartum pain was mild overall, with median rest and dynamic pain scores being less than 4 and similar between the groups. MFI and EQ-5D-5L scores were the worst on postpartum day 1 in both groups and gradually improved to antepartum level by the one-month postpartum visit. Higher MFI score on postpartum day 1, but not the use of epidural analgesia, was associated with lower odds of achieving adequate postpartum ambulation (defined as >3500 steps between 48 and 72 hours postpartum).

conclusionThe use of epidural analgesia was not associated with worse recovery outcomes during postpartum hospitalization.

trial registrationUMIN-CTR, #UMIN000039343, registered on January 31, 2020.

Indexed as

Analgesia, EpiduralAnalgesia, ObstetricalDelivery, ObstetricFemaleHumansPainParityPregnancyProspective StudiesQuality of Life

Identifiers

PMID37797060
PMCPMC10553803
OpenAlexW4387362305

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.