Evidence map›Paper›PMID 37796780›Full record

ArticlePloS one2023

Seroprevalence of SARS-CoV-2 IgG among healthcare workers in Lagos, Nigeria.

Fehintola Anthonia Ige, Gregory Aigbe Ohihoin, Kazeem Osuolale, Adedamola Dada, Ngozi Onyia, Adeyemi Johnson, Azuka Patrick Okwuraiwe, Omoladun Odediran, Gideon Liboro, Maureen Aniedobe and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Fehintola Anthonia IgeCenter for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.ORCID 0000-0002-6257-614X
Gregory Aigbe OhihoinClinical Science Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Kazeem OsuolaleMonitoring and Evaluation Unit, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Adedamola DadaFederal Medical Center, Ebute-Metta, Lagos Nigeria.
Ngozi OnyiaPaelon Memorial Medical Center, Victoria Island, Lagos, Nigeria.
Adeyemi JohnsonFirst Cardiology Consultants, Ikoyi, Lagos, Nigeria.
Azuka Patrick OkwuraiweCenter for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Omoladun OdediranBody Soul and Spirit Project, Department of Community Health and Primary Care College of Medicine, University of Lagos, Lagos, Nigeria.ORCID 0000-0003-0677-8182
Gideon LiboroCenter for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Maureen AniedobeClinical Diagnostic Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Sunday MogajiFederal Medical Center, Ebute-Metta, Lagos Nigeria.
Stephanie Ogechi NwaiwuCenter for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Ibukun Ruth AkandeCenter for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Rosemary Ajuma AuduCenter for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Babatunde Lawal SalakoClinical Science Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Nigerian Institute of Medical Research · NGFirst Consultants Medical Center · NGUniversity of Lagos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthcare workers (HCWs) are disproportionately infected with SARS-CoV-2 when compared to members of the general public; estimating the seroprevalence of SARS-CoV-2 antibody and SARS-CoV-2 infection rate among HCWs is therefore crucial. This study was carried out in four health facilities in Lagos Nigeria to determine the prevalence of IgG antibodies (seroprevalence) and SARS-CoV-2 active infection rate via a positive rtPCR result, the cross-sectional study was conducted between December 2020 and July 2021. Nasopharyngeal and blood samples were collected from HCWs and screened for SARS-CoV-2 infection using the rtPCR technique and antibody using the Abbott anti-SARS-CoV-2 IgG CMIA assay, respectively. Demographic and occupational exposures data were obtained and analysed using descriptive and inferential statistics, variables significant via inferential statistics were subjected to a multivariate analysis. A total of 413 participants were enrolled, with a mean age in years of 38.4±11.0. The seroprevalence was 30.9% (115/372) while 63/395 (15.9%) were actively infected with the virus. HCWs whose job role had direct contact with patients had a higher percentage of SARS-CoV-2 infection when compared with those not in direct contact, also being a health care worker was significantly associated with getting a positive COVID-19 PCR result. In conclusion the SARS-CoV-2 seroprevalence seen in this study was higher than national serosurvey estimates indicating HCWs are at higher risk of COVID-19 infection when compared to the general public. Vaccination and effective implementation of infection control measures are important to protect HCWs.

Indexed as

COVID-19SARS-CoV-2Antibodies, ViralCross-Sectional StudiesHealth PersonnelHumansImmunoglobulin GNigeriaSeroepidemiologic StudiesAntibodies, ViralImmunoglobulin G

Identifiers

PMID37796780
PMCPMC10553227
OpenAlexW4387363017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.