Evidence map›Paper›PMID 37796651›Full record

ArticleEuropean journal of psychotraumatology2023

Changes in comorbid depression following intensive trauma-focused treatment for PTSD and complex PTSD.

Paul Paridaen, Eline M Voorendonk, Georgy Gomon, Elisabeth A Hoogendoorn, Agnes van Minnen, Ad de Jongh

Open access · goldAbstract read
In one paragraph

Article in European journal of psychotraumatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Paul ParidaenResearch Department, PSYTREC, Bilthoven, the Netherlands.ORCID 0000-0002-1651-2671
Eline M VoorendonkResearch Department, PSYTREC, Bilthoven, the Netherlands.ORCID 0000-0001-7554-8343
Georgy GomonDepartment of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, the Netherlands.ORCID 0000-0002-5317-5328
Elisabeth A HoogendoornLeiden University, Leiden, the Netherlands.ORCID 0000-0002-0406-0954
Agnes van MinnenResearch Department, PSYTREC, Bilthoven, the Netherlands.ORCID 0000-0002-3099-8444
Ad de JonghResearch Department, PSYTREC, Bilthoven, the Netherlands.ORCID 0000-0001-6031-9708
Radboud University Nijmegen · NLAntes · NLLeiden University · NLLeiden University Medical Center · NLQueen's University Belfast · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe extent to which intensive trauma-focused treatment for individuals with post-traumatic stress disorder (PTSD) is also effective in treating comorbid major depressive disorder (MDD) remains unclear.

objectiveThe purpose of the present study was to test the hypothesis that brief intensive trauma-focused therapy for PTSD is associated with significant reductions in depressive symptoms and loss of diagnostic status of MDD.

methodsA total of 334 adult patients with PTSD (189 patients who were also diagnosed with MDD) underwent a brief intensive trauma-focused treatment programme consisting of EMDR therapy, prolonged exposure, physical activity, and psychoeducation. At pre-treatment, post-treatment and 6-month follow-up, severity and diagnostic status of PTSD and MDD were assessed. A linear mixed model was used to analyze changes in the severity of PTSD and depressive symptoms, whereas a generalized linear mixed model was used to determine changes in the MDD diagnostic status.

resultsTreatment resulted in a significant and strong decrease of PTSD and MDD symptoms at post-treatment (

conclusionsThe results support the notion that brief, intensive trauma-focused treatment is highly effective for individuals with PTSD and comorbid MDD. Because patients with CPTSD are vulnerable to relapse in depressive symptoms, this target group may require additional treatment.

Indexed as

Major Depressive DisorderStress Disorders, Post-TraumaticAdultDepressionHumansPsychotherapyRecurrenceComplex post-traumatic stress disorder (CPTSD)EMDR therapyEMDR治疗、延长暴露治疗、线性混合模型intensive trauma-focused treatmentlinear mixed modelmajor depressive disorder (MDD)modelo lineal mixtoprolonged exposure therapyterapia de exposición prolongadaterapia EMDRTrastorno de estrés postraumático complejo (TEPTC)Trastorno depresivo mayor (TDM)tratamiento intensivo focalizado en trauma:复杂创伤后应激障碍(CPTSD)强化创伤聚焦治疗重性抑郁障碍(MDD)

Identifiers

PMID37796651
PMCPMC10557564
OpenAlexW4387363766

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.