Evidence map›Paper›PMID 37796642›Full record

ArticleCancer journal (Sudbury, Mass.)

Hepatocellular Carcinoma Genetic Classification.

Zurabi Lominadze, Mohammed Rifat Shaik, Dabin Choi, Duha Zaffar, Lopa Mishra, Kirti Shetty

Abstract read
In one paragraph

Article in Cancer journal (Sudbury, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zurabi LominadzeFrom the Division of Gastroenterology and Hepatology, University of Maryland School of Medicine.
Mohammed Rifat ShaikDepartment of Medicine, University of Maryland Midtown Medical Center.
Dabin ChoiDepartment of Medicine, University of Maryland Medical Center, Baltimore, MD.
Duha ZaffarDepartment of Medicine, University of Maryland Midtown Medical Center.
Lopa MishraFeinstein Institutes for Medical Research and Cold Spring Harbor Laboratory, Divisions of Gastroenterology and Hepatology, Northwell Health, Manhasset, NY.
Kirti ShettyFrom the Division of Gastroenterology and Hepatology, University of Maryland School of Medicine.

Funding

Role of Beta Spectrin and Smad in Alcohol-Induced Liver and GI Cell ProliferationR01AA023146 · NIAAA · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Lopa Mishra · 2013 to 2026
$4.6M
Pathway Specific Functional Biomarkers for the Early Detection of Liver CancerU01CA230690 · NCI · GEORGE WASHINGTON UNIVERSITY · PI MISHRA, LOPA, SHETTY, KIRTI · 2018 to 2022
$3.4M
Cellular interactions between TGF-beta pathway members and epignetic regulators in liver and gastrointestinal cancersR01CA236591 · NCI · GEORGE WASHINGTON UNIVERSITY · PI Jian Chen, Lopa Mishra · 2018 to 2026
$3.0M
NCI NIH HHS R01 CA236591NCI NIH HHS U01 CA230690NIAAA NIH HHS R01 AA023146
6 · The paper itself

Abstract

abstractHepatocellular carcinoma (HCC) represents a significant global burden, with management complicated by its heterogeneity, varying presentation, and relative resistance to therapy. Recent advances in the understanding of the genetic, molecular, and immunological underpinnings of HCC have allowed a detailed classification of these tumors, with resultant implications for diagnosis, prognostication, and selection of appropriate treatments. Through the correlation of genomic features with histopathology and clinical outcomes, we are moving toward a comprehensive and unifying framework to guide our diagnostic and therapeutic approach to HCC.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsGenomicsHumans

Identifiers

PMID37796642
PMCPMC10686192

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.