Evidence map›Paper›PMID 37796535›Full record

ArticleNano letters2023

Hyper-Branched Gold Nanoconstructs for Photoacoustic Imaging in the Near-Infrared Optical Window.

Myeongsoo Kim, Don VanderLaan, Jeungyoon Lee, Ayoung Choe, Kelsey P Kubelick, Jinhwan Kim, Stanislav Y Emelianov

Abstract read
In one paragraph

Article in Nano letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  11. ACS nano · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Myeongsoo KimPetit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Don VanderLaanSchool of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Jeungyoon LeeSchool of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Ayoung ChoeWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Georgia 30332, United States.
Kelsey P KubelickWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Georgia 30332, United States.
Jinhwan KimWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Georgia 30332, United States.ORCID 0000-0003-0719-0655
Stanislav Y EmelianovPetit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.ORCID 0000-0002-7098-133X

Funding

Trimodal Vitality Imaging of Neural Progenitor Cells in the Spinal CordR01NS117613 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI EMELIANOV, STANISLAV Y · 2020 to 2025
$3.0M
Image-guided cancer therapy using heat activatable CAR T cellsR01EB032822 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI EMELIANOV, STANISLAV Y, KWONG, GABRIEL A · 2022 to 2025
$2.6M
Magnetic Steering and Longitudinal Visualization of Stem Cells for Trabecular Meshwork Therapy in GlaucomaR01EY030071 · NEI · GEORGIA INSTITUTE OF TECHNOLOGY · PI EMELIANOV, STANISLAV Y, ETHIER, C ROSS · 2019 to 2022
$2.3M
Nanoparticle-augmented image-guided CAR T therapy and post-treatment assessmentK99CA263016 · NCI · GEORGIA INSTITUTE OF TECHNOLOGY · PI KIM, JINHWAN · 2022 to 2022
$133k
NCI NIH HHS K99 CA263016NEI NIH HHS R01 EY030071NIBIB NIH HHS R01 EB032822NINDS NIH HHS R01 NS117613
6 · The paper itself

Abstract

In plasmonic nanoconstructs (NCs), fine-tuning interparticle interactions at the subnanoscale offer enhanced electromagnetic and thermal responses in the near-infrared (NIR) wavelength range. Due to tunable electromagnetic and thermal characteristics, NCs can be excellent photoacoustic (PA) imaging contrast agents. However, engineering plasmonic NCs that maximize light absorption efficiency across multiple polarization directions, i.e., exhibiting blackbody absorption behavior, remains challenging. Herein, we present the synthesis, computational simulation, and characterization of hyper-branched gold nanoconstructs (HBGNCs) as a highly efficient PA contrast agent. HBGNCs exhibit remarkable optical properties, including strong NIR absorption, high absorption efficiency across various polarization angles, and superior photostability compared to conventional standard plasmonic NC-based contrast agents such as gold nanorods and gold nanostars.

Indexed as

NeoplasmsPhotoacoustic TechniquesContrast MediaDiagnostic ImagingGoldHumansContrast MediaGoldblackbody absorptioncancer imagingexogenous contrast agentshyper-branched gold nanoconstructsphotoacoustic imaging

Identifiers

PMID37796535
PMCPMC10603794

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.