Evidence map›Paper›PMID 37796343›Full record

ArticleCurrent microbiology2023

GeneXpert Ultra in Urine Samples for Diagnosis of Extra-Pulmonary Tuberculosis.

Urvashi B Singh, K P Angitha, Anuj Bhatnagar, Sangeeta Sharma, Raunak Bir, Kiran Singh, Pamela Nabeta, Morten Ruhwald, Sushil K Kabra, Rakesh Lodha

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Diagnostic accuracy of Xpert MTB/RIF Ultra for detecting pulmonary tuberculosis and rifampicin resistance: a systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Urvashi B SinghDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, India. drurvashi@gmail.com.ORCID http://orcid.org/0000-0001-8753-9743
K P AngithaDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Anuj BhatnagarDepartment of Tuberculosis and Chest Diseases, Rajan Babu Institute for Pulmonary Medicine and Tuberculosis, New Delhi, India.
Sangeeta SharmaDepartment of Pediatrics, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
Raunak BirDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Kiran SinghDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Pamela NabetaThe global alliance for diagnostics, FIND, Geneva, Switzerland.
Morten RuhwaldThe global alliance for diagnostics, FIND, Geneva, Switzerland.
Sushil K KabraDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Rakesh LodhaDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · INFIND · CHLRS Institute of Tuberculosis and Respiratory Diseases · IN

Funding

All India Institute of Medical Sciences, New Delhi, and FIND, the global alliance for diagnostics, Geneva All India Institute of Medical Sciences, New Delhi, and FIND, the global alliance for diagnostics, Geneva
6 · The paper itself

Abstract

Extra-pulmonary tuberculosis (EPTB) continues to be difficult to diagnose. Novel biomarkers in biological specimens offer promise. Detection of Mycobacterium tuberculosis (Mtb) DNA in urine could prove useful in diagnosis of EPTB, possibly due to disseminated disease or micro-abscesses reported in kidneys. The current study was designed to detect Mtb DNA in stored urine samples from patients with EPTB. Diagnosis of EPTB was reached using Microbiological Reference Standards (MRS) on samples from the disease site using WHO Recommended Diagnostics (WRD), [smear microscopy, liquid culture (MGIT-960)] and GX (molecular WRD, mWRD) and Comprehensive reference standards [CRS, clinical presentation, microbiological reference standards, radiology, histopathology]. GX-Ultra was performed on urine samples stored in -80

Indexed as

Tuberculosis, ExtrapulmonaryDNAHumansKidneyMicroscopyRetrospective StudiesDNA

Identifiers

PMID37796343
OpenAlexW4387357833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.