Evidence map›Paper›PMID 37796286›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2023

Differences in imaging and clinical characteristics are associated with higher rates of decompression-fusion versus decompression-alone in women compared to men for lumbar degenerative spondylolisthesis.

Alex M Fong, Roland Duculan, Yoshimi Endo, John A Carrino, Frank P Cammisa, Alexander P Hughes, Darren R Lebl, James C Farmer, Russel C Huang, Harvinder S Sandhu and 3 more

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Alex M FongHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Roland DuculanHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Yoshimi EndoHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
John A CarrinoHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Frank P CammisaHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Alexander P HughesHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Darren R LeblHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
James C FarmerHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Russel C HuangHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Harvinder S SandhuHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Carol A MancusoHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA. mancusoc@hss.edu.ORCID http://orcid.org/0000-0003-1800-570X
Federico P GirardiHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Andrew A SamaHospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe goals were to ascertain if differences in imaging/clinical characteristics between women and men were associated with differences in fusion for lumbar degenerative spondylolisthesis.

methodsPatients had preoperative standing radiographs, CT scans, and intraoperative fluoroscopic images. Symptoms and comorbidity were obtained from patients; procedure (fusion-surgery or decompression-alone) was obtained from intraoperative records. With fusion surgery as the dependent variable, men and women were compared in multivariable logistic regression models with clinical/imaging characteristics as independent variables. The sample was dichotomized, and analyses were repeated with separate models for men and women.

resultsFor 380 patients (mean age 67, 61% women), women had greater translation, listhesis angle, lordosis, and pelvic incidence, and less diastasis and disc height (all p ≤ 0.03). The rate of fusion was higher for women (78% vs. 65%; OR 1.9, p = 0.008). Clinical/imaging variables were associated with fusion in separate models for men and women. Among women, in the final multivariable model, less comorbidity (OR 0.5, p = 0.05), greater diastasis (OR 1.6, p = 0.03), and less anterior disc height (OR 0.8, p = 0.0007) were associated with fusion. Among men, in the final multivariable model, opioid use (OR 4.1, p = 0.02), greater translation (OR 1.4, p = 0.0003), and greater diastasis (OR 2.4, p = 0.0002) were associated with fusion.

conclusionsThere were differences in imaging characteristics between men and women, and women were more likely to undergo fusion. Differences in fusion within groups indicate that decisions for fusion were based on composite assessments of clinical and imaging characteristics that varied between men and women.

Indexed as

Spinal FusionSpondylolisthesisAgedDecompression, SurgicalFemaleHumansLumbar VertebraeMaleRetrospective StudiesTreatment OutcomeDecompression aloneDecompression-fusionGender differencesLDSLumbar degenerative spondylolisthesis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.