Evidence map›Paper›PMID 37796278›Full record

GuidelineUrologie (Heidelberg, Germany)2023

[Conservative and pharmacological treatment of benign prostatic hyperplasia : The German S2e-guideline 2023-part2].

Thomas Bschleipfer, S Dominik Abt, Klaus F Becher, Kurt Dreikorn, Klaus Höfner, Stephan Madersbacher, Guiseppe Magistro, Rolf Muschter, Matthias Oelke, Oliver Reich and 4 more

Abstract readEnglish AbstractReviewPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Urologie (Heidelberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects of a proprietary mixture of extracts fromFrontiers in pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 4 countries.

Thomas BschleipferKlinik für Urologie und Kinderurologie, Regiomed Klinikum, Ketschendorfer Straße 33, 96450, Coburg, Deutschland. Thomas.Bschleipfer@regiomed-kliniken.de.
S Dominik AbtKlinik für Urologie, Spitalzentrum, Biel, Biel, Schweiz.
Klaus F BecherKlinik für Rehabilitation, Klinik Wartenberg Professor Dr. Selmair GmbH & Co. KG, Wartenberg, Deutschland.
Kurt DreikornUrologicum, Bremen, Deutschland.
Klaus HöfnerKlinik für Urologie, Evangelisches Krankenhaus, Oberhausen, Deutschland.
Stephan MadersbacherKlinik für Urologie und Andrologie, Klinik Favoriten, Wien, Österreich.
Guiseppe MagistroKlinik für Urologie, Asklepios Westklinikum GmbH, Hamburg, Deutschland.
Rolf MuschterUrologische Abteilung, ALTA Klinik, Bielefeld, Deutschland.
Matthias OelkeKlinik für Urologie, Urologische Onkologie und Roboter-assistierte Chirurgie, St. Antonius-Hospital GmbH, Gronau, Deutschland.
Oliver ReichUrologische Privatpraxis Prof. Dr. Oliver Reich, München, Deutschland.
Malte RiekenPraxis alta uro, Basel, Schweiz.
Johannes SalemCUROS urologisches Zentrum, Klinik LINKS VOM RHEIN, Köln, Deutschland.
Martin C MichelAbteilung Pharmakologie, Johannes-Gutenberg-Universität, Mainz, Deutschland.
Sandra SchönburgUniversitätsklinik und Poliklinik für Urologie, Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Deutschland.
Asklepios · DEEvangelisches Krankenhaus Oberhausen · DEJohannes Gutenberg University Mainz · DEKlinikum Bielefeld · DEKlinikum Brandenburg · DEKlinikum Coburg · DEMartin Luther University Halle-Wittenberg · DEPraxis · EESpitalzentrum Centre hospitalier Biel- Bienne · CHSt.-Antonius-Hospital Gronau · DEUniversitätszahnklinik Wien · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH, in German guidelines: benign prostatic syndrome [BPS]) is considered the most common disease of the lower urinary tract in men and can have a tremendous impact on the quality-of-life of affected patients. Conservative and pharmacological therapy of this disease are of great importance, both in improving LUTS and reducing progression-related complications.

objectivesPresentation of the conservative and pharmacological treatment options according to the current German S2e guideline on BPS. MATERIALS AND

methodsSummary and overview of chapters 9 and 10 of the current German S2e guideline on BPS.

resultsIn addition to a controlled watchful waiting for BPS patients without an absolute indication for prostate surgery, a variety of phytopharmacological formulations and synthetic drugs according to the symptomatology and clinical progress are available. Phytotherapy should, due to inconsistent study data, only be considered for mild to moderate symptoms. Synthetic drugs include alpha-blockers, 5α-reductase inhibitors, phosphodiesterase inhibitors, antimuscarinics and, more recently, the β3-agonist mirabegron in the current guideline. In addition, various combination therapies are listed and evaluated according to their indications, effects and side effects.

conclusionsThe current German S2e guideline on the diagnosis and treatment of BPS provides an evidence-based foundation for finding the best possible and most effective medication.

Indexed as

Lower Urinary Tract SymptomsProstatic HyperplasiaSynthetic DrugsAdrenergic alpha-AntagonistsHumansMaleProstateTreatment OutcomeAdrenergic alpha-AntagonistsSynthetic DrugsCombination therapyMedical therapyMonotherapyPhytopharmaceuticalsWatchful waiting

Identifiers

PMID37796278
OpenAlexW4387373319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.