Evidence map›Paper›PMID 37796017›Full record

Trial reportNeuro-oncology2024

Telehealth group Cognitive-Behavioral Therapy for Insomnia (CBT-I) in primary brain tumor: Primary outcomes from a single-arm phase II feasibility and proof-of-concept trial.

Ashlee R Loughan, Autumn Lanoye, Kelcie D Willis, Amber Fox, Scott G Ravyts, Alicia Zukas, Youngdeok Kim

Open access · greenAbstract readClinical Trial, Phase II
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neuro-oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ashlee R LoughanDepartment of Neurology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0003-1231-2469
Autumn LanoyeMassey Comprehensive Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0003-3705-0880
Kelcie D WillisDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.
Amber FoxDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.
Scott G RavytsDepartment of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, Maryland, USA.
Alicia ZukasDepartment of Neurosurgery, Medical College of South Carolina, Charleston, South Carolina, USA.
Youngdeok KimDepartment of Kinesiology and Health Sciences, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-6134-0100
Virginia Commonwealth University · USJohns Hopkins University · USMedical University of South Carolina · US

Funding

NRG Oncology NCORP Research Base-BIQSFPUG1CA189867 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI Deborah Watkins Bruner, Lisa A. Kachnic · 2014 to 2026
$140.5M
NCI NIH HHS UG1 CA189867
6 · The paper itself

Abstract

backgroundCognitive-Behavioral Therapy for Insomnia (CBT-I), the frontline treatment for insomnia, has yet to be evaluated among patients with primary brain tumors (PwPBT) despite high prevalence of sleep disturbance in this population. This study aimed to be the first to evaluate the feasibility, safety, and acceptability of implementing telehealth group CBT-I as well as assessing preliminary changes in subjective sleep metrics in PwPBT from baseline to follow-up.

methodsAdult PwPBT were recruited to participate in six 90-min telehealth group CBT-I sessions. Feasibility was assessed by rates of screening, eligibility, enrollment, and data completion. Safety was measured by participant-reported adverse events. Acceptability was assessed by retention, session attendance, satisfaction, recommendation of program to others, and qualitative feedback. Participant subjective insomnia severity, sleep quality, and fatigue were assessed at baseline, post intervention, and 3-month follow-up.

resultsTelehealth group CBT-I was deemed safe. Following the 76% screening rate, 85% of interested individuals met study eligibility and 98% enrolled (N = 44). Ninety-one percent of enrolled participants completed measures at baseline, 79% at post intervention, and 73% at 3-month follow-up. Overall, there was an 80% retention rate for the 6-session telehealth group CBT-I intervention. All participants endorsed moderate-to-strong treatment adherence and 97% reported improved sleep. Preliminary pre-post intervention effects demonstrated improvements in subjective insomnia severity, sleep quality, and fatigue with large effect sizes. These effects were maintained at follow-up.

conclusionsResults of this proof-of-concept trial indicate that telehealth group CBT-I is feasible, safe, and acceptable among PwPBT, providing support for future randomized controlled pilot trials.

Indexed as

Cognitive Behavioral TherapySleep Initiation and Maintenance DisordersTelemedicineAdultFatigueFeasibility StudiesHumansTreatment OutcomeCognitive–Behavioral Therapy for Insomnia (CBT-I)insomniaprimary brain tumorsleep disturbance

Identifiers

PMID37796017
PMCPMC10911999
OpenAlexW4387357994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.