Evidence map›Paper›PMID 37795982›Full record

ArticleInfection and immunity2023

A broadly immunogenic polyvalent

Siqi Li, Shaghayegh Anvari, Galen Ptacek, Ipshita Upadhyay, Robert W Kaminski, David A Sack, Weiping Zhang

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Recent progress in enterotoxigenicInfection and immunity · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Characterization ofApplied and environmental microbiology · 2025
    Article
  9. Article
  10. Article
  11. Evaluation of a multi-epitope vaccine PME forFrontiers in immunology · 2025
    Article
  12. Mapping the functional B-cell epitopes ofApplied and environmental microbiology · 2024
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Siqi LiDepartment of Pathobiology, University of Illinois at Urbana-Champaign , Urbana, Illinois, USA.
Shaghayegh AnvariDepartment of Diagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine , Manhattan, Kansas, USA.
Galen PtacekDepartment of Pathobiology, University of Illinois at Urbana-Champaign , Urbana, Illinois, USA.
Ipshita UpadhyayDepartment of Pathobiology, University of Illinois at Urbana-Champaign , Urbana, Illinois, USA.
Robert W KaminskiDepartment of Enteric Infections, Walter Reed Army Institute of Research , Silver Spring, Maryland, USA.ORCID 0000-0002-4015-5694
David A SackDepartment of International Health, Johns Hopkins University Bloomberg School of Public Health , Baltimore, Maryland, USA.
Weiping ZhangDepartment of Pathobiology, University of Illinois at Urbana-Champaign , Urbana, Illinois, USA.ORCID 0000-0002-3723-2257
University of Illinois Urbana-Champaign · USJohns Hopkins University · USKansas State University · USWalter Reed Army Institute of Research · US

Funding

A cross protective multivalent vaccine for Shigella and ETECR01AI175214 · NIAID · JOHNS HOPKINS UNIVERSITY · PI DAVID A SACK · 2023 to 2026
$3.0M
A broadly protective subunit vaccine against enterotoxigenic Escherichia coli (ETEC) associateddiarrheaR01AI121067 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI ZHANG, WEIPING · 2016 to 2020
$2.0M
NIAID NIH HHS R01 AI121067NIAID NIH HHS R01 AI175214
6 · The paper itself

Abstract

There are no licensed vaccines for

Indexed as

Dysentery, BacillaryShigellaShigella VaccinesAnimalsAntibodies, BacterialAntigens, BacterialChildDiarrheaHumansImmunoglobulin AImmunoglobulin GLungMiceShiga ToxinsShigella flexneriShigella sonneiAntibodies, BacterialAntigens, BacterialImmunoglobulin AImmunoglobulin GShiga ToxinsShigella Vaccinesbroad immunogenicitycross-protectionlethal pulmonary challengeMEFA (multiepitope fusion antigen)multivalent vaccinepolyvalent immunogenShigella

Identifiers

PMID37795982
PMCPMC10652900
OpenAlexW4387357097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.