Evidence map›Paper›PMID 37795936›Full record

ReviewThe Journal of physiology2023

Message in a bubble: the translational potential of extracellular vesicles.

H Alqurashi, M Alsharief, M L Perciato, B Raven, K Ren, D W Lambert

Abstract readReview
In one paragraph

Review in The Journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

H AlqurashiSchool of Clinical Dentistry, University of Sheffield, Sheffield, UK.ORCID 0000-0002-8726-1443
M AlshariefSchool of Clinical Dentistry, University of Sheffield, Sheffield, UK.
M L PerciatoSchool of Clinical Dentistry, University of Sheffield, Sheffield, UK.
B RavenSchool of Clinical Dentistry, University of Sheffield, Sheffield, UK.ORCID 0009-0002-8911-0398
K RenSchool of Clinical Dentistry, University of Sheffield, Sheffield, UK.
D W LambertSchool of Clinical Dentistry, University of Sheffield, Sheffield, UK.ORCID 0000-0001-9003-3145

Funding

Academy of Medical Sciences NAFR12∖1035Biotechnology and Biological Sciences Research Council BB/T508159/1Biotechnology and Biological Sciences Research Council BB/X018989/1
6 · The paper itself

Abstract

Extracellular vesicles (EVs) are small, membrane-enclosed vesicles released by cells into the extracellular milieu. They are found in all body fluids and contain a variety of functional cargo including DNA, RNA, proteins, glycoproteins and lipids, able to provoke phenotypic responses in cells, both locally and at distant sites. They are implicated in a wide array of physiological and pathological processes and hence have attracted considerable attention in recent years as potential therapeutic targets, drug delivery vehicles and biomarkers of disease. In this review we summarise the major functions of EVs in health and disease and discuss their translational potential, highlighting opportunities of - and challenges to - capitalising on our rapidly increasing understanding of EV biology for patient benefit.

Indexed as

Extracellular VesiclesBiomarkersCell CommunicationHumansProteinsBiomarkersProteinsbiomarkersclinical translationextracellular vesiclestherapeutics

Identifiers

PMID37795936
PMCPMC10952456

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.