Evidence map›Paper›PMID 37795537›Full record

ArticleAmerican journal of physiology. Renal physiology2023

Pathways and parameters of sacral neuromodulation in rats.

James A Hokanson, Christopher L Langdale, Warren M Grill

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

James A HokansonDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, United States.ORCID 0000-0002-0560-4503
Christopher L LangdaleDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, United States.ORCID 0000-0002-6704-2665
Warren M GrillDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, United States.ORCID 0000-0001-5240-6588
Duke University · USMarquette University · US

Funding

Predicting Urinary Continence Status with Sacral Neuromodulation and Botulinum Toxin TreatmentsK01DK121866 · NIDDK · MEDICAL COLLEGE OF WISCONSIN · PI HOKANSON, JAMES ARTHUR · 2020 to 2022
$392k
NIDDK NIH HHS K01 DK121866
6 · The paper itself

Abstract

The stimulation paradigm for sacral neuromodulation has remained largely unchanged since its inception. We sought to determine, in rats, whether stimulation-induced increases in bladder capacity correlated with the proportion of sensory pudendal (PudS) neurons at each stimulated location (L6, S1). If supported, this finding could guide the choice of stimulation side (left/right) and level (S2, S3, S4) in humans. Unexpectedly, we observed that acute stimulation at clinically relevant (low) amplitudes [1-1.5 × motor threshold (T

Indexed as

Electric Stimulation TherapyUrinary Bladder, OveractiveAnimalsElectric StimulationHumansObesityRatsUrinary BladderUrinationelectrical stimulationoveractive bladderpudendal nerveratsacral neuromodulation

Identifiers

PMID37795537
PMCPMC10874681
OpenAlexW4387357656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.