Evidence map›Paper›PMID 37795530›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2023

Delayed metabolic disturbances in the myocardium after exertional heat stroke: contrasting effects of exertion and thermal load.

Christian K Garcia, Bryce J Gambino, Gerard P Robinson, Michael T Rua, Jamal M Alzahrani, Thomas L Clanton

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christian K GarciaDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida, United States.
Bryce J GambinoDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida, United States.
Gerard P RobinsonDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida, United States.
Michael T RuaDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida, United States.
Jamal M AlzahraniDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida, United States.
Thomas L ClantonDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida, United States.ORCID 0000-0003-0600-7150
University of Florida · US

Funding

Breathing Research and Therapeutics (BREATHE)T32HL134621 · NHLBI · UNIVERSITY OF FLORIDA · PI Gordon S. Mitchell · 2017 to 2026
$3.4M
NHLBI NIH HHS T32 HL134621
6 · The paper itself

Abstract

Epidemiological studies report higher risks of cardiovascular disease in humans exposed to heat stroke earlier in life. Previously, we explored mechanistic links between heat stroke and developing cardiac abnormalities using a preclinical mouse model of exertional heat stroke (EHS). Profound metabolic abnormalities developed in the ventricles of females but not males after 2 wk of recovery. Here we tested whether this lack of response in males could be attributed to the lower exercise performances or reduced thermal loads they experienced with the same running protocol. We systematically altered environmental temperature (T

Indexed as

Heat StrokePhysical ExertionAdultAnimalsBody TemperatureFemaleHumansMaleMiceMice, Inbred C57BLMyocardiumheart diseaseheat stresshyperthermiametabolic flexibilitymetabolomics

Identifiers

PMID37795530
PMCPMC10979828
OpenAlexW4387356785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.