Evidence map›Paper›PMID 37795409›Full record

SynthesisFrontiers in medicine2023

Acute kidney injury in patients with COVID-19 compared to those with influenza: a systematic review and meta-analysis.

Chiu-Ying Hsiao, Heng-Chih Pan, Vin-Cent Wu, Ching-Chun Su, Tzu-Hsuan Yeh, Min-Hsiang Chuang, Kuan-Chieh Tu, Hsien-Yi Wang, Wei-Chih Kan, Chun-Chi Yang and 1 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Anthraquinones fromDrug design, development and therapy · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Chiu-Ying HsiaoDivision of Nephrology, Department of Internal Medicine, Chi-Mei Medical Center, Tainan, Taiwan.
Heng-Chih PanGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Vin-Cent WuDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Ching-Chun SuDivision of Nephrology, Department of Internal Medicine, Chi-Mei Medical Center, Tainan, Taiwan.
Tzu-Hsuan YehDivision of Nephrology, Department of Internal Medicine, Chi-Mei Medical Center, Tainan, Taiwan.
Min-Hsiang ChuangDivision of Nephrology, Department of Internal Medicine, Chi-Mei Medical Center, Tainan, Taiwan.
Kuan-Chieh TuDivision of Cardiology, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Hsien-Yi WangDivision of Nephrology, Department of Internal Medicine, Chi-Mei Medical Center, Tainan, Taiwan.
Wei-Chih KanDivision of Nephrology, Department of Internal Medicine, Chi-Mei Medical Center, Tainan, Taiwan.
Chun-Chi YangDivision of Hepato-gastroenterology, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Jui-Yi ChenDepartment of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan, Taiwan.
Chi Mei Medical Center · TWChang Gung University · TWChia Nan University of Pharmacy and Science · TWChung Hwa University of Medical Technology · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: COVID-19 and influenza can both lead to acute kidney injury (AKI) as a common complication. However, no meta-analysis has been conducted to directly compare the incidence of AKI between hospitalized patients with COVID-19 and influenza. The objective of our study aims to investigate the incidence and outcomes of AKI among hospitalized patients between these two groups. Materials and methods: A systematic search of PubMed, Embase, and Cochrane databases was conducted from December 2019 to August 2023 to identify studies examining AKI and clinical outcomes among hospitalized patients with COVID-19 and influenza. The primary outcome of interest was the incidence of AKI, while secondary outcomes included in-hospital mortality, recovery from AKI, hospital and ICU stay duration. The quality of evidence was evaluated using Cochrane and GRADE methods. Results: Twelve retrospective cohort studies, involving 17,618 hospitalized patients with COVID-19 and influenza, were analyzed. COVID-19 patients showed higher AKI incidence (29.37% vs. 20.98%, OR: 1.67, 95% CI 1.56-1.80, Conclusion: COVID-19 patients had higher risk of developing AKI, experiencing in-hospital mortality, and enduring prolonged hospital/ICU stays in comparison to influenza patients. Additionally, the likelihood of AKI recovery was lower among COVID-19 patients.

Indexed as

acute kidney injuryCOVID-19influenzamortalityrecovery

Identifiers

PMID37795409
PMCPMC10547056
OpenAlexW4386892983

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.