ArticleEndoscopic ultrasound
EUS-guided therapies for primary and secondary prophylaxis in gastric varices-An updated systematic review and meta-analysis.
Article in Endoscopic ultrasound. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Risk Factors for Rebleeding After Endoscopic Injection of Cyanoacrylate Glue for Gastric Varices: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2024Pooled it
- Gastric varices: a contemporary review of vascular anatomy and therapeutic strategies.BMJ open gastroenterology · 2026Review
- Endoscopic ultrasound-guided coil-assisted retrograde transgastric occlusion of shunt efferent for gastric variceal bleeding.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026Article
- Endoscopic ultrasound-guided coil embolization and absorbable hemostatic gelatin sponge is a safe and efficacious treatment for bleeding rectal varices.iGIE : innovation, investigation and insights · 2026Article
- The evolving role of endoscopic ultrasound from diagnosis to therapy in hepatic vascular interventions.Frontiers in medicine · 2026Review
- Endoscopic ultrasound-guided coil embolization for gastric varices: A promising alternative to traditional therapies.World journal of gastrointestinal endoscopy · 2025Review
- Endohepatology: Current perspectives and future directions.Hepatology communications · 2025Review
- Endoscopic ultrasound-guided therapies in the treatment of gastric varices: An in-depth examination of associated adverse events.World journal of gastrointestinal endoscopy · 2024Article
- Comprehensive approach to esophageal variceal bleeding: From prevention to treatment.World journal of gastroenterology · 2024Article
- EUS-Guided Vascular Interventions: Recent Advances.Journal of clinical medicine · 2024Review
- Role of albumin-bilirubin score in non-malignant liver disease.World journal of gastroenterology · 2024Article
- EUS-Guided Combined Injection Therapy as a Secondary Prophylaxis of Gastric Variceal Bleeding in a Patient Contraindicated for TIPS: Case Report.Medicina (Kaunas, Lithuania) · 2024Article
- Endoscopic ultrasound in portal hypertension: navigating venous hemodynamics and treatment efficacy.Gastroenterology report · 2024Review
Corrections and comments
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Authors and funding
12 authors at 10 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objectives: Gastric varices (GVs) are associated with a higher risk of uncontrolled bleeding and death when compared with esophageal varices. While endoscopic glue injection therapy has been traditionally used for secondary prophylaxis in GV, data regarding primary prophylaxis continue to emerge. Recently, EUS-guided therapies have been used in GV bleeding. Methods: We conducted a comprehensive search of several major databases from inception to June 2022. Our primary goals were to estimate the pooled rates of treatment efficacy, GV obliteration, GV recurrence, and rebleeding with EUS-guided therapy in primary and secondary prophylaxis. Overall adverse events and technical failures were assessed. Random-effects model was used for our meta-analysis, and heterogeneity was assessed using the Results: Eighteen studies with 604 patients were included. In primary prophylaxis, pooled rate of GV obliteration was 90.2% (confidence interval [CI], 81.1-95.2; Conclusion: Our analysis shows that EUS-guided therapy for GVs is technically feasible and clinically successful in both primary and secondary prophylaxis of GV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.