Evidence map›Paper›PMID 37795340›Full record

ArticleHardwareX2023

OptoPi: An open source flexible platform for the analysis of small animal behaviour.

Xavier Cano-Ferrer, Ruairí J V Roberts, Alice S French, Joost de Folter, Hui Gong, Luke Nightingale, Amy Strange, Albane Imbert, Lucia L Prieto-Godino

Abstract read
In one paragraph

Article in HardwareX, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xavier Cano-FerrerThe Francis Crick Institute, London NW1 1BF, United Kingdom.
Ruairí J V RobertsThe Francis Crick Institute, London NW1 1BF, United Kingdom.
Alice S FrenchThe Francis Crick Institute, London NW1 1BF, United Kingdom.
Joost de FolterThe Francis Crick Institute, London NW1 1BF, United Kingdom.
Hui GongThe Francis Crick Institute, London NW1 1BF, United Kingdom.
Luke NightingaleThe Francis Crick Institute, London NW1 1BF, United Kingdom.
Amy StrangeThe Francis Crick Institute, London NW1 1BF, United Kingdom.
Albane ImbertThe Francis Crick Institute, London NW1 1BF, United Kingdom.
Lucia L Prieto-GodinoThe Francis Crick Institute, London NW1 1BF, United Kingdom.

Funding

Wellcome Trust CC2067
6 · The paper itself

Abstract

Behaviour is the ultimate output of neural circuit computations, and therefore its analysis is a cornerstone of neuroscience research. However, every animal and experimental paradigm requires different illumination conditions to capture and, in some cases, manipulate specific behavioural features. This means that researchers often develop, from scratch, their own solutions and experimental set-ups. Here, we present OptoPi, an open source, affordable (∼ £600), behavioural arena with accompanying multi-animal tracking software. The system features highly customisable and reproducible visible and infrared illumination and allows for optogenetic stimulation. OptoPi acquires images using a Raspberry Pi camera, features motorised LED-based illumination, Arduino control, as well as irradiance monitoring to fine-tune illumination conditions with real time feedback. Our open-source software (BioImageProcessing) can be used to simultaneously track multiple unmarked animals both in on-line and off-line modes. We demonstrate the functionality of OptoPi by recording and tracking under different illumination conditions the spontaneous behaviour of larval zebrafish as well as adult

Indexed as

3D-printingArduinoBehaviourLaser cuttingLEDLight stimulationNeuroscienceOpen hardwareOptogenetics

Identifiers

PMID37795340
PMCPMC10545942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.