Evidence map›Paper›PMID 37795206›Full record

ReviewInfection and drug resistance2023

Understanding Post-Sepsis Syndrome: How Can Clinicians Help?

Elisabeth C van der Slikke, Lise F E Beumeler, Madlene Holmqvist, Adam Linder, Robert T Mankowski, Hjalmar R Bouma

Open access · goldAbstract readReview
In one paragraph

Review in Infection and drug resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Trajectories of sepsis survivors in Australia: A scoping review.Journal of the Intensive Care Society · 2026
    Article
  6. Measuring health-related quality of life in sepsis survivors and caregivers: a mapping review and a preliminary conceptual framework.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Current standard of care for septic shock.Intensive care medicine · 2026
    Review
  12. Review
  13. Article
  14. Article
  15. Supplementation with GPR120 (Ffar4) ligand omega-3 does not improve survival in murine sepsis models.American journal of physiology. Endocrinology and metabolism · 2025
    Article
  16. Sympathetic regulation of the host immune response to bacterial sepsis.Clinical science (London, England : 1979) · 2025
    Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Elisabeth C van der SlikkeDepartment of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, the Netherlands.ORCID 0000-0001-5055-0332
Lise F E BeumelerDepartment of Intensive Care, Medical Centre Leeuwarden, Leeuwarden, 8934AD, the Netherlands.ORCID 0000-0002-6513-3635
Madlene HolmqvistDepartment of Infection Medicine, Skåne University Hospital Lund, Lund, 221 84, Sweden.
Adam LinderDepartment of Infection Medicine, Skåne University Hospital Lund, Lund, 221 84, Sweden.
Robert T MankowskiDepartment of Physiology and Aging, University of Florida, Gainesville, FL, 32610, USA.
Hjalmar R BoumaDepartment of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, the Netherlands.ORCID 0000-0003-1032-321X
Skåne University Hospital · SEUniversity Medical Center Groningen · NLUniversity of Florida · USUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is a global health challenge, with over 49 million cases annually. Recent medical advancements have increased in-hospital survival rates to approximately 80%, but the escalating incidence of sepsis, owing to an ageing population, rise in chronic diseases, and antibiotic resistance, have also increased the number of sepsis survivors. Subsequently, there is a growing prevalence of "post-sepsis syndrome" (PSS). This syndrome includes long-term physical, medical, cognitive, and psychological issues after recovering from sepsis. PSS puts survivors at risk for hospital readmission and is associated with a reduction in health- and life span, both at short and long term, after hospital discharge. Comprehensive understanding of PSS symptoms and causative factors is vital for developing optimal care for sepsis survivors, a task of prime importance for clinicians. This review aims to elucidate our current knowledge of PSS and its relevance in enhancing post-sepsis care provided by clinicians.

Indexed as

long-term outcomepost-sepsis syndromesepsis

Identifiers

PMID37795206
PMCPMC10546999
OpenAlexW4387189725

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.