Evidence map›Paper›PMID 37794871›Full record

ArticleEuropean heart journal. Digital health2023

An artificial intelligence tool for automated analysis of large-scale unstructured clinical cine cardiac magnetic resonance databases.

Jorge Mariscal-Harana, Clint Asher, Vittoria Vergani, Maleeha Rizvi, Louise Keehn, Raymond J Kim, Robert M Judd, Steffen E Petersen, Reza Razavi, Andrew P King and 2 more

Open access · goldAbstract read
In one paragraph

Article in European heart journal. Digital health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Jorge Mariscal-HaranaSchool of Biomedical Engineering & Imaging Sciences Rayne Institute, 4th Floor, Lambeth Wing St. Thomas' Hospital Westminster Bridge Road London SE1 7EH.
Clint AsherSchool of Biomedical Engineering & Imaging Sciences Rayne Institute, 4th Floor, Lambeth Wing St. Thomas' Hospital Westminster Bridge Road London SE1 7EH.
Vittoria VerganiSchool of Biomedical Engineering & Imaging Sciences Rayne Institute, 4th Floor, Lambeth Wing St. Thomas' Hospital Westminster Bridge Road London SE1 7EH.
Maleeha RizviSchool of Biomedical Engineering & Imaging Sciences Rayne Institute, 4th Floor, Lambeth Wing St. Thomas' Hospital Westminster Bridge Road London SE1 7EH.
Louise KeehnDepartment of Clinical Pharmacology, King's College London British Heart Foundation Centre, St Thomas' Hospital, London, Westminster Bridge Road, London SE1 7EH, UK.ORCID https://orcid.org/0000-0002-2486-9056
Raymond J KimDivision of Cardiology, Department of Medicine, Duke University, 40 Duke Medicine Circle, Durham, NC 27710, USA.
Robert M JuddDivision of Cardiology, Department of Medicine, Duke University, 40 Duke Medicine Circle, Durham, NC 27710, USA.
Steffen E PetersenWilliam Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.ORCID https://orcid.org/0000-0003-4622-5160
Reza RazaviSchool of Biomedical Engineering & Imaging Sciences Rayne Institute, 4th Floor, Lambeth Wing St. Thomas' Hospital Westminster Bridge Road London SE1 7EH.ORCID https://orcid.org/0000-0003-1065-3008
Andrew P KingSchool of Biomedical Engineering & Imaging Sciences Rayne Institute, 4th Floor, Lambeth Wing St. Thomas' Hospital Westminster Bridge Road London SE1 7EH.ORCID https://orcid.org/0000-0002-9965-7015
Bram RuijsinkSchool of Biomedical Engineering & Imaging Sciences Rayne Institute, 4th Floor, Lambeth Wing St. Thomas' Hospital Westminster Bridge Road London SE1 7EH.
Esther Puyol-AntónSchool of Biomedical Engineering & Imaging Sciences Rayne Institute, 4th Floor, Lambeth Wing St. Thomas' Hospital Westminster Bridge Road London SE1 7EH.ORCID https://orcid.org/0000-0002-9789-6629
St Thomas' Hospital · GBDuke University · USTuring Institute · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Aims: Artificial intelligence (AI) techniques have been proposed for automating analysis of short-axis (SAX) cine cardiac magnetic resonance (CMR), but no CMR analysis tool exists to automatically analyse large (unstructured) clinical CMR datasets. We develop and validate a robust AI tool for start-to-end automatic quantification of cardiac function from SAX cine CMR in large clinical databases. Methods and results: Our pipeline for processing and analysing CMR databases includes automated steps to identify the correct data, robust image pre-processing, an AI algorithm for biventricular segmentation of SAX CMR and estimation of functional biomarkers, and automated post-analysis quality control to detect and correct errors. The segmentation algorithm was trained on 2793 CMR scans from two NHS hospitals and validated on additional cases from this dataset ( Conclusion: We show that our proposed tool, which combines image pre-processing steps, a domain-generalizable AI algorithm trained on a large-scale multi-domain CMR dataset and quality control steps, allows robust analysis of (clinical or research) databases from multiple centres, vendors, and cardiac diseases. This enables translation of our tool for use in fully automated processing of large multi-centre databases.

Indexed as

Artificial intelligenceCardiac functionCardiac magnetic resonanceCardiac segmentationQuality control

Identifiers

PMID37794871
PMCPMC10545512
OpenAlexW4384130567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.