Evidence map›Paper›PMID 37794711›Full record

Trial reportESC heart failure2023

Hypoxaemic burden in heart failure patients receiving adaptive servo-ventilation.

Mathias Baumert, Dominik Linz, Michael Pfeifer, Maria Tafelmeier, Philippe Felfeli, Michael Arzt, Sobhan S Shahrbabaki

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in ESC heart failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Mathias BaumertDiscipline of Biomedical Engineering, School of Electrical and Mechanical Engineering, The University of Adelaide, Adelaide, SA, 5005, Australia.ORCID 0000-0003-2984-2167
Dominik LinzDepartment of Cardiology, Maastricht University Medical Centre and Cardiovascular Research Institute, Maastricht, The Netherlands.
Michael PfeiferDepartment of Pneumology, Donaustauf Hospital, Donaustauf, Germany.
Maria TafelmeierDepartment of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.
Philippe FelfeliDepartment of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.
Michael ArztDepartment of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.
Sobhan S ShahrbabakiDiscipline of Biomedical Engineering, School of Electrical and Mechanical Engineering, The University of Adelaide, Adelaide, SA, 5005, Australia.
University Hospital Regensburg · DEThe University of Adelaide · AUKlinik Donaustauf · DEUniversity of Copenhagen · DK

Funding

Else-Kroener Fresenius FoundationPhilips Home Healthcare SolutionsPhilips RespironicsResMed Foundation
6 · The paper itself

Abstract

aimsThis study aimed to assess the effectiveness of adaptive servo-ventilation (ASV) for lowering hypoxaemic burden components in heart failure with reduced ejection fraction (HFrEF) patients. METHODS AND

resultsFifty-six stable HFrEF patients with left ventricular ejection fraction ≤ 40 were randomized to receive either ASV (n = 27; 25 males) or optimal medical management or optimal medical management alone (n = 29; 26 males). Patients underwent overnight polysomnography at baseline and a 12 week follow-up visit. We quantified hypoxaemic as time spent at <90% oxygen saturation (T90) decomposed into desaturation-related components (T90

conclusionsASV effectively suppresses the sleep apnoea-related component of hypoxaemic burden in HFrEF patients. A significant hypoxaemic burden not directly attributable to sleep apnoea but related to the severity of heart failure remains and may adversely affect cardiovascular long-term outcomes.

Indexed as

Heart FailureSleep Apnea SyndromesHumansLungMaleStroke VolumeTreatment OutcomeVentricular Function, LeftAdaptive servo-ventilationHeart failure with sleep apnoeaRandomized controlled trial

Identifiers

PMID37794711
PMCPMC10682887
OpenAlexW4387357973

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.