ArticleSubstance abuse treatment, prevention, and policy2023
A cost benefit analysis of a virtual overdose monitoring service/mobile overdose response service: the national overdose response service.
Article in Substance abuse treatment, prevention, and policy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 13 citations in OpenAlex.
- "We're here, and we're non-judgmental, we're here to save lives": stressors and fulfillment among overdose response hotline operators in Canada.Harm reduction journal · 2026Article
- Article
- Beyond REMS & PDMPs: A Proposed Framework for Next-Generation Opioid Regulation.Therapeutic innovation & regulatory science · 2026Review
- "I think that that really could benefit a lonely user:" perceptions of overdose response hotlines among people who use opioids.Harm reduction journal · 2025Article
- "It's something we're connected to": Acceptability and adoption of overdose detection technologies implemented in San Francisco permanent supportive housing.Journal of substance use and addiction treatment · 2025Article
- "Oh, Another Overdose, for the Love of Pete": First Responder Perspectives on Overdose Response Technology.The western journal of emergency medicine · 2025Article
- Cost savings of EMS administration of bronchodilators and systemic corticosteroids for pediatric asthma patients.Frontiers in public health · 2025Article
- Perceptions of overdose response hotlines and applications among rural and remote individuals who use drugs in Canada: a qualitative study.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2024Article
- Accessibility gaps of physical supervised consumption sites in Canada motivating the use of overdose response technology/phone based virtual overdose response services: a retrospective cohort study.Lancet regional health. Americas · 2024Article
- Implementing Canada's first national virtual phone based overdose prevention service: lessons learned from creating the National Overdose Response Service (NORS).Harm reduction journal · 2024Article
- Preference for hotline versus mobile application/countdown-based mobile overdose response services: a qualitative study.Harm reduction journal · 2024Article
- Virtual overdose monitoring services/mobile overdose response services: estimated number of potentially averted drug poisoning fatality events by various telephone and digital-based overdose prevention/harm reduction services in North America.Frontiers in public health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThe overdose crisis continues across Canada which calls for novel harm reduction strategies. Previous research indicates that a majority of eHealth solutions are cost-effective however current literature on the cost-benefit of eHealth for harm reduction is sparse. The National Overdose Response Service (NORS) is a Canada-wide telephone-based harm reduction service. Service users can call the phone number and connect to a peer who can virtually monitor the substance use session and dispatch appropriate interventions in the case of overdose. OBJECTIVES OF THE RESEARCH/PROJECT: We aim to assess the cost-benefit of NORS by comparing the estimated cost-savings from prevented overdose mortality to the operating costs of the program, alongside healthcare costs associated with its operation.
methodsData around systems costs and operational costs were gathered for our calculations. Our primary outcome was cost-benefit ratios, derived from estimates and models of mortality rates in current literature and value of life lost. We presented our main results across a range of values for costs and the probability of death following an unwitnessed overdose. These values were utilized to calculate cost-benefit ratios and value per dollar spent on service provision by NORS over the length of the program's operation (December 2020-2022).
resultsOver the total funded lifespan of the program, and using a Monte Carlo estimate, the benefit-to-cost ratio of the NORS program was 8.59 (1.53-15.28) per dollar spent, depending on estimated mortality rates following unwitnessed overdose and program operation costs. Further, we conservatively estimate that early community-based naloxone intervention results in healthcare system savings of $4470.82 per overdose response.
conclusionsWe found the NORS program to have a positive benefit-to-cost ratio when the probability of death following an unwitnessed overdose was greater than 5%. NORS and potentially other virtual overdose monitoring services have the potential to be cost-effective solutions for managing the drug poisoning crisis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.