Evidence map›Paper›PMID 37794450›Full record

ArticleVeterinary research2023

Detection of classical BSE prions in asymptomatic cows after inoculation with atypical/Nor98 scrapie.

Marina Betancor, Belén Marín, Alicia Otero, Carlos Hedman, Antonio Romero, Tomás Barrio, Eloisa Sevilla, Jean-Yves Douet, Alvina Huor, Juan José Badiola and 2 more

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Classical BSE emergence from Nor98/atypical scrapie: Unraveling the shift vs. selection dichotomy in the prion field.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Marina BetancorCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2, Universidad de Zaragoza, 50013, Zaragoza, Spain.
Belén MarínCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2, Universidad de Zaragoza, 50013, Zaragoza, Spain.
Alicia OteroCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2, Universidad de Zaragoza, 50013, Zaragoza, Spain. aliciaogar@unizar.es.ORCID http://orcid.org/0000-0001-9075-2764
Carlos HedmanCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2, Universidad de Zaragoza, 50013, Zaragoza, Spain.
Antonio RomeroServicio de Cirugía y Medicina Equina, Hospital Veterinario, Universidad de Zaragoza, 50013, Zaragoza, Spain.
Tomás BarrioUMR INRAE ENVT 1225 Interactions Hôtes-Agents Pathogènes, École Nationale Vétérinaire de Toulouse, 31076, Toulouse, France.
Eloisa SevillaCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2, Universidad de Zaragoza, 50013, Zaragoza, Spain.
Jean-Yves DouetUMR INRAE ENVT 1225 Interactions Hôtes-Agents Pathogènes, École Nationale Vétérinaire de Toulouse, 31076, Toulouse, France.
Alvina HuorUMR INRAE ENVT 1225 Interactions Hôtes-Agents Pathogènes, École Nationale Vétérinaire de Toulouse, 31076, Toulouse, France.
Juan José BadiolaCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2, Universidad de Zaragoza, 50013, Zaragoza, Spain.
Olivier AndréolettiUMR INRAE ENVT 1225 Interactions Hôtes-Agents Pathogènes, École Nationale Vétérinaire de Toulouse, 31076, Toulouse, France.
Rosa BoleaCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Instituto Agroalimentario de Aragón - IA2, Universidad de Zaragoza, 50013, Zaragoza, Spain.
Universidad de Zaragoza · ESÉcole Nationale Vétérinaire de Toulouse · FR

Funding

Ministerio de Ciencia e Innovación PID2021-125398OB-I00POCTEFA EFA148/16
6 · The paper itself

Abstract

The emergence of bovine spongiform encephalopathy (BSE) prions from atypical scrapie has been recently observed upon experimental transmission to rodent and swine models. This study aimed to assess whether the inoculation of atypical scrapie could induce BSE-like disease in cattle. Four calves were intracerebrally challenged with atypical scrapie. Animals were euthanized without clinical signs of prion disease and tested negative for PrP

Indexed as

Cattle DiseasesEncephalopathy, Bovine SpongiformPrion DiseasesPrionsScrapieSheep DiseasesSwine DiseasesAnimalsBrainCattleFemaleSheepSwinePrionsatypical scrapiebovine spongiform encephalopathyPrionPrPSc

Identifiers

PMID37794450
PMCPMC10548751
OpenAlexW4387342029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.