ReviewEuropean journal of medical research2023
Orbital inflammatory pseudotumor: new advances in diagnosis, pathogenesis, and treatment.
Review in European journal of medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 29 citations in OpenAlex.
- Idiopathic Granulomatous Inflammation of the Periocular Structures in Four Dogs: Clinical, Histopathological, and Imaging Findings and Therapeutic Outcome.Veterinary ophthalmology · 2026Article
- Idiopathic Orbital Inflammation Masquerading as Relapse of Seronegative Juvenile Myasthenia Gravis: A Case Report.Journal of paediatrics and child health · 2026Article
- Article
- Exploring the Etiologies of Acquired Unilateral Proptosis: A Literature Review with Case Presentations.Archives of plastic surgery · 2026Article
- Bilateral orbital pseudotumor as the initial manifestation of granulomatosis con poliangeítis (GPA) in a child: A case report.Radiology case reports · 2026Article
- Case Report: Thoracic SMARCA4-deficient undifferentiated tumor with extraocular muscle metastasis: a rare case hidden in diplopia.Frontiers in medicine · 2026Article
- A Possible Association Between Gluten Sensitivity and Idiopathic Orbital Inflammation: A Case Report.Cureus · 2025Article
- Clinical features and recurrence patterns of pediatric idiopathic orbital inflammatory disease.BMC ophthalmology · 2025Article
- Serum Biomarkers Linked to Disease Activity, Severity, and Methylprednisolone Response in Graves' Orbitopathy: A Proteomic Study.Investigative ophthalmology & visual science · 2025Article
- IgG4-Related Orbital Disease vs. Idiopathic Orbital Inflammation: Clinical Features, Therapy and Outcomes in a Central-European Retrospective Single-Center Cohort.Biomedicines · 2025Article
- Outcomes of Volumetric-Modulated Arc Therapy for Refractory, Corticosteroid-Resistant Orbital Inflammatory Diseases.Advances in radiation oncology · 2025Article
- Orbital Myositis as a Paradoxical Reaction to Anti-Tuberculosis TreatmentBalkan medical journal · 2025Article
- Metastatic melanoma to the orbit masquerading as idiopathic orbital inflammation: a case report.Frontiers in ophthalmology · 2025Article
- Quantitative evaluation of fibrosis in idiopathic orbital inflammatory pseudotumor by IVIM-DWI.Frontiers in ophthalmology · 2025Article
- Efficacy of low-dose rituximab versus immunosuppressants in refractory orbital inflammatory pseudotumors with intracranial extension.Frontiers in immunology · 2025Article
- Article
- [Invasive ENT infections in immunocompetent schoolchildren in the winter half year 2022/23 : A case series].Wiener medizinische Wochenschrift (1946) · 2024Article
- Nonspecific Orbital Inflammation (NSOI): Unraveling the Molecular Pathogenesis, Diagnostic Modalities, and Therapeutic Interventions.International journal of molecular sciences · 2024Review
- Bone destruction of orbital wall in idiopathic orbital inflammatory pseudotumor: does it always imply malignancy?International journal of ophthalmology · 2024Article
- Idiopathic Posterior Scleritis Complicated by Optic Perineuritis and Ocular Motility Disorder Successfully Controlled with Adalimumab: A Case Report.Case reports in ophthalmologyArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Orbital inflammatory pseudotumor (OIP) is a benign, non-specific inflammatory disorder that commonly occurs in middle-aged adults and is usually unilateral but can occur bilaterally. Its clinical manifestations have tremendous clinical heterogeneity and vary according to the site of infiltration and the degree of lesions, including orbital pain, swelling, diplopia, proptosis, restricted eye movement, and decreased visual acuity. Clinical features, Image characteristics and pathological examinations often need to be evaluated to confirm the diagnosis. Currently, there is no systematic research on the pathogenesis of OIP, which may be related to immunity or infection. The first-line treatment is glucocorticoids. Radiotherapy, immunosuppressants, and biologics can be considered for treatment-resistant, hormone-dependent, or intolerant patients. In this review, we aim to summarize and focus on new insights into OIP, including new diagnostic criteria, pathogenesis, and discoveries in new drugs and treatment strategies. In particular, we highlight the literature and find that T cell-mediated immune responses are closely related to the pathogenesis of OIP. Further exploration of the mechanism and signaling pathway of T cells in the immune process will help to identify their therapeutic targets and carry out targeted therapy to treat refractory OIP and reduce the side effects of traditional treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.