Evidence map›Paper›PMID 37794320›Full record

ArticleBMC neurology2023

Design of the STEPS trial: a phase II randomized controlled trial evaluating eHealth-supported motor-cognitive home training for Parkinson's disease.

Breiffni Leavy, Jenny Sedhed, Elke Kalbe, Elisabet Åkesson, Erika Franzén, Hanna Johansson

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05510739 (Support for Physical Activity in Everyday Life With Parkinson's Disease Using eHealth Technology), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05510739 nacompletednot on this map

Support for Physical Activity in Everyday Life With Parkinson's Disease Using eHealth Technology

TypeinterventionalSponsorStiftelsen Stockholms SjukhemRan2022 to 2025Enrolled138ConditionsParkinson Disease, Physical Activity, eHealth, Gait Disorders, NeurologicArmsMotor-cognitive home exercise supported by eHealth technology, Individualized home exercise program
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Breiffni LeavyDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden. breiffni.leavy@ki.se.
Jenny SedhedDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.
Elke KalbeMedical Psychology | Neuropsychology and Gender Studies & Centre for Neuropsychological Diagnostics and Intervention (CeNDI), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Elisabet ÅkessonStockholm Sjukhem Foundation, Research and development unit, Stockholm, Sweden.
Erika FranzénDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.
Hanna JohanssonDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.
Swedish Foundation for Strategic Research · SEKarolinska Institutet · SEUniversity Hospital Cologne · DE

Funding

Forskningsrådet om Hälsa, Arbetsliv och Välfärd STY-2023/0004NEURO Sweden F2022-0052ParkinsonFörbundet 133/21Stiftelsen Promobilia A22117Stockholm sjukhem foundation PRJ18-0005Stockholms Läns Landsting FoUI-974072The Kamprad family foundation 20210201
6 · The paper itself

Abstract

backgroundElectronic health (eHealth) technology offers the potential to support and motivate physical activity for symptom management in Parkinson's disease (PD). It is also recommended that motor exercise in PD be complemented with cognitive training aimed at attentional or executive functions. This paper describes the protocol for a double-blind randomized controlled trial to evaluate the effects of motor-cognitive training in the home environment, supported by eHealth. METHODS/

designThe Support for home Training using Ehealth in Parkinsons diseaSe (STEPS) is a double-blind single center randomized controlled trial. Two parallel groups will include in total 120 participants with mild to moderate PD who will receive either (i) the intervention (a progressive 10-week individualized motor-cognitive eHealth training with cognitive behavioral elements to increase physical activity levels) or (ii) an active control group (an individualized 10-week paper-based home exercise program). The active control group will not receive motor-cognitive exercises or cognitive behavioral approaches to increase physical activity level. The primary outcome is walking capacity assessed by the six-minute walk test (6MWT). Secondary outcomes will include gait performance during single and dual task conditions, gait speed, functional mobility and lower limb strength, balance, physical activity behavior and a range of patient reported outcome measures relevant in PD. DISCUSSION: The STEPS trial will answer the question whether 10 weeks of eHealth supported motor-cognitive exercise in the home environment can improve walking capacity in PD when compared to a standard paper exercise program. Findings from this study will also strengthen the evidence concerning the efficacy of PD-specific eHealth interventions with a view meeting future health care demands by addressing issues of inaccessibility to specialized neurological rehabilitation in PD.

trial registrationClinicalTrials.gov August 2022, NCT05510739.

Indexed as

Parkinson DiseaseTelemedicineClinical Trials, Phase II as TopicCognitionExercise TherapyGaitHumansRandomized Controlled Trials as TopicWalkingeHealthHome exerciseMotor-cognitive exerciseParkinson’s diseasePhysical activity

Identifiers

PMID37794320
PMCPMC10548709
OpenAlexW4387339917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.