ArticleThe ISME journal2023
Protistan predation selects for antibiotic resistance in soil bacterial communities.
Article in The ISME journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Review
- Predation in microbial communities: gradients of nutritive killing.Nature reviews. Microbiology · 2026Review
- Article
- Article
- Predator-mediated local convergence fosters global microbial community divergence.Nature communications · 2026Article
- Cross-domain cooperation drives nutrient acquisition and metabolism in the bark beetle holobiont.The ISME journal · 2026Article
- Viral and eukaryotic drivers of prokaryotic and antibiotic resistance gene diversity in wastewater microbiomes.Microbiome · 2026Article
- Selective shifts in mobile antibiotic resistance genes under carbamazepine exposure in wastewater microbiomes.ISME communications · 2026Article
- Effects of predatory mite biocontrols on the dispersal of antibiotic resistomes and virulence factors in tea garden soils.Microbiome · 2025Article
- Article
- Protozoa-enhanced conjugation frequency alters the dissemination of soil antibiotic resistance.The ISME journal · 2025Article
- Use of PGPB in bio-fertilisation: preserving the soil microbiome and enhancing field production of alfalfa.Frontiers in microbiology · 2025Article
- Regulation of Antibiotic Resistance Genes on Agricultural Land Is Dependent on Both Choice of Organic Amendment and Prevalence of Predatory Bacteria.Antibiotics (Basel, Switzerland) · 2024Article
- Protist predation selects for the soil resistome.The ISME journal · 2024Article
- Predatory protists impact plant performance by promoting plant growth-promoting rhizobacterial consortia.The ISME journal · 2024Article
- Protist predation promotes antimicrobial resistance spread through antagonistic microbiome interactions.The ISME journal · 2024Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding how antibiotic resistance emerges and evolves in natural habitats is critical for predicting and mitigating antibiotic resistance in the context of global change. Bacteria have evolved antibiotic production as a strategy to fight competitors, predators and other stressors, but how predation pressure of their most important consumers (i.e., protists) affects soil antibiotic resistance genes (ARGs) profiles is still poorly understood. To address this gap, we investigated responses of soil resistome to varying levels of protistan predation by inoculating low, medium and high concentrations of indigenous soil protist suspensions in soil microcosms. We found that an increase in protistan predation pressure was strongly associated with higher abundance and diversity of soil ARGs. High protist concentrations significantly enhanced the abundances of ARGs encoding multidrug (oprJ and ttgB genes) and tetracycline (tetV) efflux pump by 608%, 724% and 3052%, respectively. Additionally, we observed an increase in the abundance of numerous bacterial genera under high protistan pressure. Our findings provide empirical evidence that protistan predation significantly promotes antibiotic resistance in soil bacterial communities and advances our understanding of the biological driving forces behind the evolution and development of environmental antibiotic resistance.
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