Evidence map›Paper›PMID 37794101›Full record

ReviewLeukemia2023

European LeukemiaNet laboratory recommendations for the diagnosis and management of chronic myeloid leukemia.

Nicholas C P Cross, Thomas Ernst, Susan Branford, Jean-Michel Cayuela, Michael Deininger, Alice Fabarius, Dennis Dong Hwan Kim, Katerina Machova Polakova, Jerald P Radich, Rüdiger Hehlmann and 3 more

Abstract readReview
In one paragraph

Review in Leukemia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nicholas C P CrossFaculty of Medicine, University of Southampton, Southampton, UK. ncpc@soton.ac.uk.ORCID 0000-0001-5481-2555
Thomas ErnstKlinik für Innere Medizin II, Universitätsklinikum Jena, Jena, Germany.ORCID 0000-0003-2147-489X
Susan BranfordCentre for Cancer Biology and SA Pathology, Adelaide, SA, Australia.
Jean-Michel CayuelaLaboratory of Hematology, University Hospital Saint-Louis, AP-HP and EA3518, Université Paris Cité, Paris, France.
Michael DeiningerHuntsman Cancer Center Salt Lake City, Salt Lake City, UT, USA.ORCID 0000-0002-2987-1331
Alice FabariusIII. Medizinische Klinik, Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim, Germany.
Dennis Dong Hwan KimDepartment of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Canada.ORCID 0000-0003-2640-4911
Katerina Machova PolakovaInstitute of Hematology and Blood Transfusion, Prague, Czech Republic.ORCID 0000-0002-7398-5555
Jerald P RadichFred Hutchinson Cancer Center, Seattle, WA, USA.ORCID 0000-0002-1618-230X
Rüdiger HehlmannIII. Medizinische Klinik, Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim, Germany.
Andreas HochhausKlinik für Innere Medizin II, Universitätsklinikum Jena, Jena, Germany.ORCID 0000-0003-0626-0834
Jane F ApperleyCentre for Haematology, Imperial College London, London, UK.ORCID 0000-0002-1710-1794
Simona SoveriniDepartment of Medical and Surgical Sciences, Institute of Hematology "Lorenzo e Ariosto Seràgnoli", University of Bologna, Bologna, Italy.ORCID 0000-0002-4508-0353

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From the laboratory perspective, effective management of patients with chronic myeloid leukemia (CML) requires accurate diagnosis, assessment of prognostic markers, sequential assessment of levels of residual disease and investigation of possible reasons for resistance, relapse or progression. Our scientific and clinical knowledge underpinning these requirements continues to evolve, as do laboratory methods and technologies. The European LeukemiaNet convened an expert panel to critically consider the current status of genetic laboratory approaches to help diagnose and manage CML patients. Our recommendations focus on current best practice and highlight the strengths and pitfalls of commonly used laboratory tests.

Indexed as

Leukemia, Myelogenous, Chronic, BCR-ABL PositiveProtein Kinase InhibitorsHumansRecurrenceProtein Kinase Inhibitors

Identifiers

PMID37794101
PMCPMC10624636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.